Receptor activity-modifying proteins (RAMPs) are single-transmembrane proteins that transport the calcitonin receptor-like receptor (CRLR) to the cell surface. RAMP 1-transported CRLR is a calcitonin gene-related peptide (CGRP) receptor. RAMP 2- or RAMP 3-transported CRLR is an adrenomedullin receptor. The role of RAMPs beyond their interaction with CRLR, a class II G protein-coupled receptor, ...

In this paper, we attempt to construct practical secret sharing schemes, which scheme has smaller share size and can detect cheating with high probability. We de ne two secure ramp schemes, secure ramp scheme and strongly secure ramp scheme. Then, we propose two constructions of secure ramp scheme. These schemes both have small share size and the cheating can be detected with high probability. ...

The pulmonary oxygen uptake (VO2) response to incremental-ramp cycle ergometry typically demonstrates lagged-linear first-order kinetics with a slope of ~10-11 ml·min(-1)·W(-1), both above and below the lactate threshold (θL), i.e. there is no discernible VO2 slow component (or "excess" VO2) above θL. We were interested in determining whether a reverse ramp profile would yield the same response...

Ramp metering is an effective, viable, and practical strategy used to manage freeway traffic. It is a proven freeway management technique as various forms of ramp control have been in place since the 1960s in the Chicago, Detroit, and Los Angeles areas. Due in part to the success of these early applications, ramp metering has received increased emphasis in recent years under the umbrella of adv...

Three experiments, each using 280 pigs, were conducted in a simulated compartment to test the effect of angle of entrance (AOE) to the ramp (90°, 60°, 30°, or 0°), ramp slope (0°, 16°, 21°, or 26°), and an initial 20-cm step associated with 16° or 21° ramp slopes on the ease of handling, heart rate (HR), and behavior of near market-weight pigs during unloading. Heart rate (pigs and handler), un...

BACKGROUND Maximal incremental exercise testing should be completed within 8-12 minutes. The ramp-slope influences the exercise duration. Oxygen-cost diagram (OCD) is a scoring scale for the capability of daily activity performed and therefore can be used to estimate the ramp-slope. METHODS The OCD-algorithm and the reported-algorithm were used prospectively in random order for selecting opti...

In times when product life cycles are decreasing, while market demands are increasing, manufacturing enterprises are confronted with the challenge of more frequent and more complex ramp-ups. Thus it becomes obvious that ramp-up management is going to be a topic enterprises have to focus on in the future. Since each ramp-up is unique concerning the product, the process, the technology, the circu...

Ramp rates for incremental ramp rate exercise testing are not standardised. The ramp rate may influence the values obtained during exercise testing. We compared a slow ramp rate (SR) (3watts/minute) to a fast ramp rate (FR) (20 watts/minute) in 8 fit non elite cyclists using cycle ergometry. We measured peak power ,oxygen consumption (VO2) at anaerobic threshold (AT) and maximum aerobic capacit...

In 1996, Jackson and Martin [10] proved that a strong ideal ramp scheme is equivalent to an orthogonal array. However, there was no good characterization of ideal ramp schemes that are not strong. Here we show the equivalence of ideal ramp schemes to a new variant of orthogonal arrays that we term augmented orthogonal arrays. We give some constructions for these new kinds of arrays, and, as a c...