Transgene silencing, which is common in transgenic plants and animals, limits the generation and application of genetically modified organisms, and is associated with the exogenous gene copy number, the methylation status of its promoters, and histone modification abnormalities. Here, we analyzed the expression of the exogenous gene DsRed and the methylation status of its cytomegalovirus (CMV) ...

Estimation of genetic parameters for horn traits and essential economic in Inner Mongolia Cashmere goats | Lei Zhang, Fenghong Wang, Lingtian Fengting Hongfu Liu, Libing He, Jinquan Li, Rui Su Agricultural Journals

Novel circRNAs from cashmere goats: Discovery, integrated regulatory network, and their putative roles in the regeneration growth of secondary hair follicles | Jincheng Shen, Yanru Wang, Man Bai, Yixing Fan, Zeying Wenlin Bai Agricultural Journals

The reproductive techniques of potential use to goat breeders have been developed in other species, notably the sheep, and have been applied to goats with only minor modifications necessitated by species differences. The Angora industry, and to a lesser extent the cashmere industry, have lent themselves readily to the relatively widespread use of reproductive techniques because of three major f...

the effect of melatonin and bromocryptine on body weight, fibre shedding and cashmere traits was investigated by using 24 raeini female goats (2-3 years old) in four experimental groups: control (c); melatonin (mi) implant (18 mg at first and repeated after 40 days), bromocryptine (b) injection, (0.5 mg/kg bw per three days) melatonin and bromocryptine implant and injection (mib). all goats wer...

Cashmere goat (Capra hircus) hair follicle development and cycling can be divided into three stages: anagen, catagen and telogen. To elucidate the genes involved in hair follicle development and cycling in cashmere goats, transcriptome profiling of skin was carried out by analysing samples from three hair follicle developmental stages using RNA-Seq. The RNA-Seq analysis generated 8487344, 81425...

We looked for novel genetic variations within the Six6 gene by PCR-SSCP, DNA sequencing and forced RFLP-PCR and estimated their associations with production traits in 2132 goats of eight indigenous Chinese breeds. A novel single nucleotide polymorphism (NM_001104993.1: g.232T>C) within the goat Six6 gene was identified. The frequencies of allele "C" varied from 0.8621 to 1.000, which were...

Here, we studied hair follicle development of Liaoning Cashmere goats. Every month for 1 year, skin samples were collected from five 1.5-year-old female goats, and made into paraffin sections. A number of parameters were measured of primary and secondary hair follicles via microscopic observation including follicle depth, hair bulb width, dermis and epidermis thickness, changes in follicle acti...