background: vitamin d, especially its most active metabolite 1,25-dihydroxyvitamin d₃(vit d) is essential in regulating a wide variety of biologic processes, such as regulating mesangial cell activation. the objective of this study was to assess the histopathological changes of effectiveness of vit d as a protective agent against radiation induced lung injury. materials and methods: eighteen wi...

This is a case report on stereotaxic (Stereotactic Body Radiotherapy-SBRT) for lung cancer located in the left lower lobe (Segment 6, S6). There have been no reports on marked displacement of the peripheral lung cancer during radiotherapy. A pulmonary nodule was discovered on computed tomography (CT) conducted for a persistent cough in an 87-year-old male. According to diagnostic imaging, this ...

radiotherapy is an important modality in the treatment of lung cancer. in australia, up to 76% of patients have an indication for radiotherapy at diagnosis. this includes curative radiotherapy for patients with inoperable stage i and ii non-small cell lung cancer, and in combination with chemotherapy, for patients with stage iii non-small cell lung cancer and limited stage small cell lung cance...

Although the application of radiotherapy techniques reduced normal lung tissue of exposure for patients with non-small cell lung cancer, Radioactive Pneumonia (RP) and Pulmonary Fibrosis (RF) are still frequently occurred in the processes of lung cancer radiotherapy. Plasminogen Activator Inhibitor-1 (PAI-1) plays a crucial role in the process of lung injury during RP in lung cancer patients. H...

Introduction: In external beam radiotherapy each effort is done to deliver 3D dose distribution onto the tumor volume uniformly, while minimizing the dose to healthy organs at the same time. Radiation treatment of tumors located at thorax region such as lung and liver has a challenging issue during target localization since these tumors move mainly due to respiration. There are...

abstract background: chest wall irradiation for early breast cancer affects forced vital capacity (fvc), forced expiratory volume in the first second of expiration (fev1) and may change peripheral oxygen saturation (spo2). in our institute chest wall is irradiated with a four field technique: two tangential and two oppositional anterior and posterior supraclavicular fields. regional recurrence ...

Background: Radiation-induced lung injury is a refractory side effect in lung cancer radiotherapy, the mechanism still remains unclear, hence an appropriate animal mode may become useful to investigate it. Materials and Methods: 50 female Wistar rats were randomly divided into 5 groups, average 10 rats/cage: A. control group B. 3Gy×10f C. 6Gy×5f D. 12.5Gy×1f E.15.3Gy×1f....

Background: Vitamin D, especially its most active metabolite 1,25-dihydroxyvitamin D₃(Vit D) is essential in regulating a wide variety of biologic processes, such as regulating mesangial cell activation. The objective of this study was to assess the histopathological changes of effectiveness of Vit D as a protective agent against radiation induced lung injury. Materials and Methods: Eighteen Wi...

Introduction: The purpose in this study is to analyze of DVH parameters as predictors of radiation pneumonitis and investigation on the relationship between dosimetric and clinical parameters based on PFTs as response in NTCP model and therefore achieve to lung dose- response relation in breast cancer patients. Prescribed dose to treatment volumes was 50 Gy in 2.0 Gy/fractions ...

introduction low-grade endometrial stromal sarcoma (lg-ess) is a malignant intrauterine tumor that rarely presents with distant metastasis. simultaneous lung and cardiac metastases from lg-ess is also an extremely rare event. case presentation a 42-year-old woman presented with dyspnea and exercise intolerance. she had a history of hysterectomy and left salpingoophorectomy. she underwent second...