(Figure 2). Given the Mobitz II second degree AVB and the bifascicular block, a bi-chamber pacemaker was implanted. Acquired AVB in young patients is a very exceptional disorder. The patient presented here had two factors that might account for the AVB: radiotherapy and hypothyroidism.1,2,4,5 Atrioventricular block secondary to hypothyroidism4 is an unusual entity that is due to the myxedematou...

BACKGROUND The purpose of this study was to determine the incidence of hypothyroidism after chemoradiation in head and neck squamous cell cancer (HNSCC). METHODS One hundred twenty-two patients treated with 3-dimensional conformal radiotherapy (3DCRT; 70 Gy/35#) or intensity-modulated radiation therapy (IMRT; 66 Gy/30#) in 2 identical simultaneous randomized trials were studied. Thyroid funct...

BACKGROUND The aim of this study was to identify the long-term clinical outcome of definitive radiotherapy using three-dimensional conformal radiotherapy (3DCRT) for cervical esophageal squamous cell carcinoma (CESCC). METHODS We retrospectively reviewed the medical records of 30 patients with CESCC [clinical stage I/II/III/IV(M1LYM); 3/2/12/13] (TNM 7th edition) who underwent definitive radi...

Thyroid hormones play essential roles in mammalian life, especially in neurodevelopment (Porterfield & Hendrich, 1993). This fact is clearly shown in patients with neurological deficits from endemic cretinism, who reside in iodine-deficient areas (DeLong et at., 1985). In addition to neurological impairments, thyroid dysfunctions, such as hyperthyroidism and hypothyroidism, lead to a wide varie...

Background & Aims of the Study: The purpose of this study, was association of environmental factors of hypothyroidism in pregnant women in Abadan during 2016. Materials and Methods: In this descriptive research, 600 women were chosen according to random – stratified sampling. For this purpose at first an information form had been made then the files of pregnant women were ...

BACKGROUND Since childhood cancer survival has increased, long-term effects of treatment have gained interest. Childhood Hodgkin's lymphoma has been treated successfully for decades now. We provide an overview of the literature on long-term endocrine side effects, such as gonadal dysfunction and growth retardation, as a result of childhood Hodgkin's lymphoma treatment. METHODS A comprehensive ...

THE 3 ORIGINAL PAPERS ARE 1. Rønjom MF, Brink C, Bentzen SM, Hegedüs L, Overgaard J, Johansen J. Hypothyroidism after primary radiotherapy for head and neck squamous cell carcinoma: normal tissue complication probability modeling with latent time correction. Radiother Oncol. 2013 Nov;109(2):317-22. 2. Rønjom MF, Brink C, Lorenzen EL, Hegedüs L, Johansen J. Variation of normal tissue complicatio...

INTRODUCTION The purpose of this study is to evaluate the possible predictors of thyroid disorders after neck radiotherapy, with a focus on radiation dose-volume factors. METHODS Thyroid function was measured in 100 patients who had received radiotherapy to the neck, including the thyroid. All radiation-induced thyroid dysfunctions were determined with an endpoint of abnormal thyroid stimulat...

Thyroid volume reduction was observed, among 25 subjects off-therapy after Hodgkin's disease. The volume reduction was related to dose (p = 0.014) and time from radiotherapy (p = 0.01). The correlation was very specific since all patients with reduced volume had hypothyroidism, but not very sensitive since 25% of subjects with thyroid dysfunction had normal gland volume.

OBJECTIVE Hematological malignancies encompass a large spectrum of disease entities whose treatment by chemo/radiotherapy could lead to thyroid complications. To the best of our knowledge, no study has simultaneously addressed thyroid function, autoimmunity and nodularity. Therefore, we decided to conduct one. MATERIALS AND METHODS We evaluated 82 Caucasian patients (36 women and 46 men), who...