There has been an increased interest in 165Dy radiossynovectomy, which emits relatively high-energy (> 1 MeV) beta rays. The production of in vivo bremsstrachlung radiation hazards warrants evaluation. The bremsstrahlung component of the decay scheme of 165Dy has been traditionally ignored in internal dosimetry calculations. We have estimated the bremsstrahlung dose of 165Dy distributed in musc...

This paper reviews the preparation and application of radioactive microspheres for medical purposes. It first discusses the properties of relevant radioisotopes and then explores the diagnostic uses of gammaemitter labeled microspheres, such as blood flow measurement and imaging of the liver and other organs. The therapeutic uses of alphaand beta-emitting microspheres, such as radioembolization...

introduction: developing new radiosynovectomy agents is of great importance due to the aging of human populations around the world and increasing the incidence of inflammatory diseases. in this work, sm-153 chitosan agent was developed for the first time in our country and preparation and quality control of the compound is described. methods: sm-153 chloride was obtained by thermal neutron flu...

OBJECTIVE(S) In this work a new possible agent for radiosynovectomy has been targeted for articular pain palliation. MATERIALS AND METHODS Lu-177 of 2.6-3 GBq/mg specific activity was obtained by irradiation of natural Lu2O3 sample with thermal neutron flux of 4 × 10(13) n.cm(-2).s(-1). The product was converted into chloride form which was further used for labeling of (177)Lu-phytate complex...

Radiosynovectomy (RSV) is a local intraarticular injection of radionuclides in colloidal form for radiotherapy. First used by Fellinger et al. in 1952, the technique has now been applied for more than 50 y for treatment of resistant synovitis of individual joints after failure of long-term systemic pharmacotherapy and intraarticular steroid injections. RSV relieves pain and inflammation from rh...

OBJECTIVE Camptodactyly-arthropathy-coxa-vara-pericarditis (CACP) syndrome is an autosomal recessive disorder caused by mutations in PRG4 gene that encodes for proteoglycan 4, the main lubricant for joints and tendon surfaces. It is a non-inflammatory arthropathy, characterized by joint effusions and synovial hypertrophy. So far, there is no effective treatment for this disorder. To evaluate th...

OBJECTIVE We aimed to assess the role of Magnetic Resonance Imaging (MRI) and X-Ray in the evaluation of response to radiosynovectomy (RS) in patients with hemophilic arthropathy. MATERIAL AND METHODS Eleven patients who suffered from hemophilic arthropathy with a mean age of 11.7 (range between 7-15) were included in this study. 148-185 MBq Yttrium 90 silicate (Y-90) was administered intraar...

  Introduction: Developing new radiosynovectomy agents is of great importance due to the aging of human populations around the world and increasing the incidence of inflammatory diseases. In this work, Sm-153 chitosan agent was developed for the first time in our country and preparation and quality control of the compound is described. Methods: Sm-153 chloride was ob...