نتایج جستجو برای: radioprotective effects

تعداد نتایج: 1544760  

2017
Zhong-Tang Li Li-Mei Wang Li-Rong Yi Chao Jia Fan Bai Ren-Jun Peng Zu-Yin Yu Guo-Lin Xiong Shuang Xing Ya-Jun Shan Ri-Fang Yang Jun-Xing Dong Yu-Wen Cong

α-tocopherol succinate (α-TOS), γ-tocotrienol (GT3) and δ-tocotrienol (DT3) have drawn large attention due to their efficacy as radioprotective agents. α-TOS has been shown to act superior to α-tocopherol (α-TOH) in mice by reducing lethality following total body irradiation (TBI). Because α-TOS has been shown to act superior to α-tocopherol (α-TOH) in mice by reducing lethality following total...

Journal: :Journal of agricultural and food chemistry 2006
M J Del Baño J Castillo O Benavente-García J Lorente R Martín-Gil C Acevedo M Alcaraz

The radioprotective effects of carnosic acid (CA), carnosol (COL), and rosmarinic acid (RO) against chromosomal damage induced by gamma-rays, compared with those of L-ascorbic acid (AA) and the S-containing compound dimethyl sulfoxide (DMSO), were determined by use of the micronucleus test for antimutagenic activity, evaluating the reduction in the frequency of micronuclei (MN) in cytokinesis-b...

Journal: :Arhiv za higijenu rada i toksikologiju 2006
Nevenka Kopjar Slavica Miocić Snjezana Ramić Mirta Milić Tomislav Viculin

Radioprotective effects of amifostine and melatonin as well as their ability to modulate the level of spontaneous and gamma-irradiation-induced genetic changes on human peripheral blood lymphocytes were investigated using the cytokinesis-block micronucleus (CBMN) assay and sister chromatid exchange (SCE). Parallel blood samples were pre-treated with amifostine, melatonin and their combination f...

Journal: :Molecules 2017
Michal Hofer Zuzana Hoferová Daniel Depeš Martin Falk

The goal of combined pharmacological approaches in the treatment of the acute radiation syndrome (ARS) is to obtain an effective therapy producing a minimum of undesirable side effects. This review summarizes important data from studies evaluating the efficacy of combining radioprotective agents developed for administration prior to irradiation and therapeutic agents administered in a post-irra...

Journal: :journal of cell and molecular research 0
farhang haddad ali moghimi abbas salmani mohammad farhad rahimi mohammad reza gawam-nasiri

study of the different aspects of protection against the exposure of ionizing radiation has always been an active area of research. high cost and toxicity of radioprotective drugs have limited their use. so, search for new drugs with a high degree of protection and lower cost and side effects seem a necessity. in this study radioprotective effect of aqueous as well as alcoholic extracts of the ...

2014
Wenqing Xu Fujun Yang Xiu Shen Saijun Fan Qiang Liu Dezhi Wang

In this study, WPT-A, a type of water-soluble homogeneous lichen polysaccharide, was isolated and purified from Parmelia tinctorum. We investigated whether WPT-A has radioprotective effects when administered before total-body irradiation (TBI). Mice were treated with WPT-A via intraperitoneal injection (i.p.) once per day for three consecutive days prior to 7, 7.5, 8.5, 10 or 10.5-Gy TBI. Our r...

Journal: :iranian journal of radiation research 0
m.r. adhvaryu bapalal vaidya botanical research centre, department of biosciences, veer narmad south gujarat university, surat, india s.p. srivastav lion's cancer research centre, new civil hospital campus, surat, india s.n. vaniawala genelab (nabl-dst), genetic research wing, shreenath pathology laboratories, surat, india m.n. reddy bapalal vaidya botanical research centre, department of biosciences, veer narmad south gujarat university, surat, india

background: synthetic radio-protective agents like aminothiols are toxic and fda approved agent amifostine is no exception. some ayurvedic herbs have shown radioprotective potential. this study was carried out to test and compare the radioprotective potential of curcuma longa (cl) tinospora cordifolia (tc), zizyphus mauritiana (zm) and ocimum sanctum (os) against 2gy gamma irradiation in swiss ...

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