A priori probability density functions characterising patterns which are imprecise spatially and with regard to amplitude (fuzzy pattern:;) and which are anticipated to be present in a radioisotopic source field were developed for use in Bayesian image processing ( B I P ) . Corresponding iterative imaging algorithms were derived using the expectation maximisation ( E M ) technique of Dempster ...

Abstract Accelerator-produced radioisotopes are widely used in modern medicine, for imaging, cancer therapy, and combinations of therapy diagnostics (theragnostics). Clinical trials well advanced several radioisotope-based treatments that might open the way to a strong request specific accelerator systems dedicated radioisotope production. While cyclotrons standard tool this domain, we explore ...

[18f]kf, considered as a reference standard for positron emission tomography of the skeletal system, was produced by the bombardment of enriched water ([18o]h2o>95%) with high energy protons in nrcam cyclotron. after the extraction of fluoride from enriched water as kf, and passing it through microbial filter and fine adjustment of acidity and osmolality, it was converted into an injectable for...

Increased expression of cellular membrane bound glucose-regulated protein 78 (GRP78) is considered to be one of the biomarkers for gastric cancers. Therefore, peptides or molecules with specific recognition to GRP78 can act as a guiding probe to direct conjugated imaging agents to localized cancers. Based on this rationale, GRP78-guided polymeric micelles were designed and manufactured for nucl...

objective(s): use of a positron emission tomography (pet)/single-photonemission computed tomography (spect) system facilitates the simultaneousacquisition of images with fluorine-18 fluorodeoxyglucose (18f-fdg) andtechnetium (99mtc)-tetrofosmin. however, 18f has a short half-life, and 511kev compton-scattered photons are detected in the 99mtc energy window.therefore, in this study, we aimed to ...