PURPOSE Men with apparently localized prostate cancer often relapse years after radical prostatectomy. We sought to determine if epithelial-like cells identified from bone marrow in patients after radical prostatectomy, commonly called disseminated tumor cells (DTC), were associated with biochemical recurrence. EXPERIMENTAL DESIGN We obtained bone marrow aspirates from 569 men prior to radica...

Aims of study Laparoscopic radical prostatectomy for prostate cancer has been gaining wider acceptance as an alternative procedure to open radical prostatectomy. The laparoscopic surgery have been reported to be less invasive and expected to give more favorable impacts on postoperative urinary continence as compared with the open procedure. However, the precise impacts of the laparoscopic proce...

How to join PubMed Commons J Urol. 2005 Jun;173(6):1848-9. Eliminating the current Bell curve to improve the results of radical prostatectomy. Nelson JB. Comment on The effect of hospital volume on cancer control after radical prostatectomy. [J Urol. 2005] Variations among high volume surgeons in the rate of complications after radical prostatectomy: further evidence that technique matters. [J ...

[2] Trock BJ, Han M, Freedland SJ, et al. Prostate cancer-specific survival following salvage radiotherapy vs observation in men with biochemical recurrence after radical prostatectomy. JAMA2008;299: 2760–9. [3] Stephenson AJ, Shariat SF, Zelefsky MJ, et al. Salvage radiotherapy for recurrent prostate cancer after radical prostatectomy. JAMA 2004; 291:1325–32. [4] Thompson IM, Tangen CM, Parade...

background: presence of discordance between the gleason score on needle biopsy and the score of radical prostatectomy specimen is common and universal. in this study, we determined the accuracy of gleason grading of biopsies in predicting histological grading of radical prostatectomy specimens and the degree of overgrading and undergrading of prostatic adenocarcinoma in our center, which is one...

PURPOSE Anastomotic strictures are relatively common after radical prostatectomy and are associated with significant morbidity, often requiring multiple surgical interventions. There is controversy in the literature regarding which factors predict the development of anastomotic strictures. In this study we determined predictors of symptomatic anastomotic strictures following contemporary radica...

BACKGROUND To investigate the risk of second cancer and radiation induced second cancer following prostate cancer radiotherapy. METHODS We compared men with radiotherapy only with those treated with radical prostatectomy only and those with radiotherapy after radical prostatectomy. Cumulative incidences of second cancers were calculated. Cox analyses were performed to identify determinants in...

Our objective was to determine the effect of neoadjuvant hormonal therapy on the presence of circulating prostate cells in patients undergoing radical prostatectomy for prostate cancer. A total of 60 patients at high risk for extraprostatic disease were analyzed for the presence of circulating prostate cells using reverse transcriptase PCR (RTPCR) amplification of the prostate-specific antigen ...

PURPOSE Robot-assisted surgery has been rapidly adopted in the U.S. for prostate cancer. Its adoption has been driven by market forces and patient preference, and debate continues regarding whether it offers improved outcomes to justify the higher cost relative to open surgery. We examined the comparative effectiveness of robot-assisted vs open radical prostatectomy in cancer control and surviv...