نتایج جستجو برای: radiation pneumonitis

تعداد نتایج: 243394  

Journal: :Clinical advances in hematology & oncology : H&O 2011
Mariam P Korah Anthony F Waller Eduard Schreibmann Walter J Curran Ian R Crocker

The efficacy of radiation treatment for intrathoracic malignancy is limited by the development of radiationinduced lung injury (RILI), which can cause radiation pneumonitis and fibrosis in the lung parenchyma. Several factors influence the risk and severity of RILI, including the radiation dose, the fractionation, the volume of irradiated lung, and whether the patient has pre-existing lung dise...

2016
Xingsheng Hu Wenwu He Shimin Wen Xuqin Feng Xi Fu Yusong Liu Ke Pu

INTRODUCTION There are no adequate data to determine whether intensity-modulated radiotherapy (IMRT) is superior to three-dimensional conformal radiotherapy (3DCRT) in the treatment of non-small cell lung cancer (NSCLC). This meta-analysis was conducted to compare the clinical outcomes of IMRT and 3DCRT in the treatment of NSCLC. METHODS No exclusions were made based on types of study design....

Journal: :Journal of Thoracic Oncology 2007

2015
Yuichi Ozawa Takefumi Abe Minako Omae Takashi Matsui Masato Kato Hirotsugu Hasegawa Yasunori Enomoto Takeaki Ishihara Naoki Inui Kazunari Yamada Koshi Yokomura Takafumi Suda Marc Vooijs

INTRODUCTION This study investigated the clinical characteristics and predictive factors for developing acute extended radiation pneumonitis with a focus on the presence and radiological characteristics of preexisting interstitial lung disease. METHODS Of 1429 irradiations for lung cancer from May 2006 to August 2013, we reviewed 651 irradiations involving the lung field. The presence, compat...

2011
Yunhai Chuai Luqian Zhao Jin Ni Ding Sun Jianguo Cui Bailong Li Liren Qian Fu Gao Jianming Cai

Radiotherapy is an important modality of cancer treatment. Radiation pneumonitis is a major obstacle to increasing the radiation dose in radiotherapy, and it is important to prevent this radiation-induced complication. Recent studies show that hydrogen has a potential as an effective and safe radioprotective agent by selectively reducing hydroxyl and peroxynitrite radicals. Since most of the io...

Journal: :Asian Pacific journal of cancer prevention : APJCP 2015
Prashanth Giridhar Supriya Mallick Goura Kishore Rath Pramod Kumar Julka

Radiation induced lung injury has long been considered a treatment limiting factor for patients requiring thoracic radiation. This radiation induced lung injury happens early as well as late. Radiation induced lung injury can occur in two phases viz. early (<6 months) when it is called radiation pneumonitis and late (>6 months) when it is called radiation induced lung fibrosis. There are multip...

Introduction: Chemoradiation is a well-established protocol for management of localized esophageal cancer. However, some early and late toxicities are associated with this therapy. Plan evaluation in term of normal tissue complication probability (NTCP) may help clinicians to tailor this therapy more individually. Given the variety of present radiobiological models, the choice...

Journal: :International journal of radiation oncology, biology, physics 2006
Graeme Morgan

Radiation pneumonitis and subsequent radiation pulmonary fibrosis are the two main dose-limiting factors when irradiating the thorax that can have severe implications for patients' quality of life. In this article, the current concepts about the pathogenetic mechanisms underlying radiation pneumonitis and fibrosis are presented. The clinical course of fibrosis, a postulated acute inflammatory s...

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