نتایج جستجو برای: r1

تعداد نتایج: 8393  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2007
Zhen Zhang Kui Yang Chin-Chuan Chen Jason Feser Mingxia Huang

Ribonucleotide reductase maintains cellular deoxyribonucleotide pools and is thus tightly regulated during the cell cycle to ensure high fidelity in DNA replication. The Sml1 protein inhibits ribonucleotide reductase activity by binding to the R1 subunit. At the completion of each turnover cycle, the active site of R1 becomes oxidized and subsequently regenerated by a cysteine pair (CX2C) at it...

Journal: :Cancer research 2008
Elise Meoli Ioannis Bossis Laure Cazabat Manos Mavrakis Anelia Horvath Sotiris Stergiopoulos Miriam L Shiferaw Glawdys Fumey Karine Perlemoine Michael Muchow Audrey Robinson-White Frank Weinberg Maria Nesterova Yianna Patronas Lionel Groussin Jérôme Bertherat Constantine A Stratakis

Most PRKAR1A tumorigenic mutations lead to nonsense mRNA that is decayed; tumor formation has been associated with an increase in type II protein kinase A (PKA) subunits. The IVS6+1G>T PRKAR1A mutation leads to a protein lacking exon 6 sequences [R1 alpha Delta 184-236 (R1 alpha Delta 6)]. We compared in vitro R1 alpha Delta 6 with wild-type (wt) R1 alpha. We assessed PKA activity and subunit e...

2005
Jianer Chen Iyad A. Kanj Ge Xia

Proof. Proceed by contradiction. Suppose that f has more than one root in (0,∞). Let r1 and r2, with r1 < r2, be two consecutive such roots (note that we can always find two consecutive roots r1 and r2 because f (r) > 0 for any root r). From the hypothesis, we have f (r1) > 0 and f (r2) > 0. Since f ′ is continuous at r1, there exists an 0 < 2 < (r2− r1) such that f (x) > 0 in the interval (r1,...

2011
Yuichi Futa Hiroyuki Okazaki Yasunari Shidama

(1) Let X be a real linear space and R1, R2 be finite sequences of elements of X. If lenR1 = lenR2, then ∑ (R1 +R2) = ∑ R1 + ∑ R2. (2) Let X be a real linear space and R1, R2, R3 be finite sequences of elements of X. If lenR1 = lenR2 and R3 = R1−R2, then ∑ R3 = ∑ R1− ∑ R2. (3) Let X be a real linear space, R1, R2 be finite sequences of elements of X, and a be an element of R. If R2 = aR1, then ...

Journal: :Journal of Mathematical Analysis and Applications 1987

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1998
F M Dautzenberg S Wille R Lohmann J Spiess

The nonselective human corticotropin-releasing factor receptor 1 (hCRF-R1) and the ligand-selective Xenopus CRF-R1 (xCRF-R1) were compared. To understand the interactions of sauvagine and ovine CRF, both high-affinity ligands for hCRF-R1 but surprisingly weak ligands for xCRF-R1, chimeric receptors of hCRF-R1 and xCRF-R1 followed by double or multiple point mutations were constructed. Binding s...

ژورنال: :زیست شناسی میکروارگانیسم ها 0
سیدحمید زرکش اصفهانی هیات علمی زهرا اعتمادی فر گروه زیست شناسی، دانشکده علوم، دانشگاه اصفهان سیمون کاپلو

مقدمه: سولفور زدایی زیستی به عنوان یک روش انتخابی برای کاهش میزان گوگرد محصولات نفتی به کار می­رود.   مواد و روش ‏‏ ها: در این تحقیق ، یک سویه باکتریایی اکسید کننده گوگرد به نام رودوکوکوس اریتروپولیس r1 (شماره دسترسی gu570564 ژن بانک ncbi ) برای سولفورزدایی از دی­بنزوتیوفن ( dbt ) استفاده شد.   نتایج : کشت القا شده سویه r1 توانایی تولید 2-هیدروکسی­بای­فنیل ( 2-hbp ) از dbt را طی مسیر 4s بدون تج...

Journal: :Asian research journal of mathematics 2023

The goal of this paper is to investigate the Generalized Hyers - Ulam Rassias (HUR) stability generalquartic functional equation (GQFE) fq(kr1 + (k -1)r2) = 2k4fq(r1) 2(k -1)4fq(r2) +6k2(k -1)2[fq(r1 r2) fq(r1 r2)] 12k2(k 1)2[fq(r1) fq(r2)] in fuzzy normed spaces (F.N. spaces). proved by using direct method. sense and Ulam- Gavruta also studied.

2011
Aruna Balasubramanian ARUNA BALASUBRAMANIAN Arun Venkataramani Brian Neil Levine

ARCHITECTING PROTOCOLS TO ENABLE MOBILE APPLICATIONS IN DIVERSE WIRELESS NETWORKS

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