Objectives: The aim of this study was to evaluate and compare the efficacy of 3 rd generation quaternary ammonium compounds and formaldehyde for fumigation of operation theatres. Materials and Methods: Fumigation and fogging of operation theatres by formaldehyde and 3 rd generation quaternary ammonium compounds respectively were done by standard procedures. A total of 144 samples (swabs as well...

The correct usage of disinfectants is an important component of a successful biosecurity program. The objective of this study was to determine the effect of time, temperature, and organic matter (OM) on disinfectant efficacy. Staphylococcus aureus and Salmonella Typhimurium were used to represent gram-negative and gram-positive bacteria commonly found in commercial poultry housing. The first st...

Materials and methods: Each model trailer was contaminated with intestinal content from a pig experimentally infected with PCV2, washed, and disinfected with one of four protocols. Between protocol steps, swabs were collected from six different areas of each trailer and tested for PCV2 DNA. Disinfection protocols were quaternary ammonium compound (DISF1), oxidizing agent containing potassium pe...

CEGLOWrSKI, W. S. (New Jersey Agricultural Experimental Station, New Brunswick, N. J.) AND S. A. LEAR. Effects of a quaternary ammonium compound on Escherichia coli. Appl. Microbiol. 10:458-462. 1962-Increasing amounts of tetradecyldimethylbenzyl ammonium chloride (TAC) were lethal to an increasing proportion of an actively growing culture of Escherichia coli. The loss of nucleic acid material ...

New dimeric, trimeric and tetrameric quaternary ammonium salts were accomplished by reaction of tertiary alkyldimethyl amines with appropriate bromomethylbenzene derivatives. A series of new cationic surfactants contain different alkyl chain lengths (C4-C18), aromatic spacers and different numbers of quaternary nitrogen atoms. The structure of the products was confirmed by spectral analysis (FT...

Contact urticaria is defined as a wheal-and-flare reaction that occurs after epicutaneous contact with a causative agent (1). Contact urticaria usually appears within minutes after contact with the causative substances, including chemicals, animal products, antibiotics and cosmetics. We report here a case of contact urticaria resulting from exposure to a disinfectant liquid spray containing eth...

OBJECTIVES Cetylpyridinium chloride (CPC), a quaternary ammonium compound, was shown to interact irreversibly with Streptococcus mutans biofilms, leading to a slow diffusion compared with poly(ethylene glycol) (PEG) molecules of similar size. The objective of this work is to determine if the retardation of CPC diffusion and its strong binding to biofilms is caused by interactions between the am...

To simulate food contact surfaces with pits or cracks, stainless steel plates with grooves (depths between 0.2 and 5 mm) were constructed. These plates were artificially contaminated with Listeria monocytogenes in clean conditions, with organic soiling, or after 14 days of biofilm formation after which inactivation of the pathogen by Suma Tab D4 (sodium dichloroisocyanurate, 240 and 300 mg/lite...

DESCRIPTION The active ingredient in ATROVENT (ipratropium bromide) Inhalation Aerosol is ipratropium bromide. It is an anticholinergic bronchodilator chemically described as 8azoniabicyclo[3.2.1]-octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1methylethyl)-, bromide, monohydrate (endo,syn)-,(±): a synthetic quaternary ammonium compound chemically related to atropine. The structural fo...

This study was designed to test in vitro efficacy of 2 improved hydrogen peroxide (HP) products against 3 standard HP products and 1 quaternary ammonium compound. Improved HP is significantly superior to standard HP at the same concentration and can be used for disinfection of environmental surfaces or noncritical patient care items.