Myocardial infarction (MI) is the leading cause of death worldwide. However, current therapies are unable to restore function injured myocardium. Advanced approaches, such as stimulation cardiomyocyte (CM) proliferation promising, but suffer from poor pharmacokinetics and possible systemic adverse effects. Nanomedicines can be a solution above-mentioned drawbacks. targeting cardiac tissue still...

In the current global scenario, in which mobility has been strongly impacted, it is relevant to highlight certain experiences of Indigenous Latin American peoples, new cultural and geographical elements justify revisiting this phenomenon. context, Aymara ethnic group offers an opportunity for such a second look. Although subject approached from perspectives internal migration processes physical...

The World Health Organization considers cigarette smoke as a major risk factor and causal agent of chronic obstructive pulmonary disease (COPD); however, smoke from biomass in poorly ventilated environments may be the major causative agent in developing countries. There is little epidemiological evidence of COPD in relation to the use of biomass fuels and altitude of the place of residence, and...

Carcinogenic and systemic health effects of arsenic exposure in drinking water are well documented. This study estimated the risk associated with chronic consumption of water with high concentrations of arsenic in children and adults living in six Andean locations, in Chile. Concentrations of arsenic in the drinking water were analyzed between 2014 and 2017 based on health authority reports and...

Several Indian Mahāyāna texts express an ethical perspective that has many features in common with Western forms of universalist consequentialism. Śāntideva, in particular, endorses a strong version of agent-neutrality, claims that compassionate agents should violate Buddhist moral commitments when doing so would produce good results, praises radical altruism, uses a critique of the self to sup...