Progressive pigmentary purpura or Schamberg's disease. Pigmented purpuric lichenoid dermatitis of Gougerot and Blum red/brown papules and plaques in men which responds to psoralen combined with ultraviolet A (PUVA) treatment. Purpura annularis telangiectodes rare, with a preponderance in young females and manifests as annular erythematous plaques and patches. Eczematoid-like purpura of Doucas a...

Five patients with purpura hyperglobulinaemia are reviewed. One patient developed ulcerative colitis; female members of this patient's family suffered from rheumatoid arthritis. The family showed immunoglobulin abnormalities. Although the clinical picture of purpura hyperglobulinaemia and Henoch-Schonlein purpura can show some common features, the former may well be separated as a 'disturbed-to...

Hematologic abnormali"es are generally present among systemic lupus erythematosus pa"ents. Idiopathic thrombocytopenic purpura can be the first manifesta"on of SLE, followed by other symptoms and signs of disease appearing several years later. Although bleeding due to immune thrombocytopenic purpura is usually mild and occurs in mucocutaneous surfaces, but it may be severe and represent in u...

endoscopic finding in Henoch–Schönlein purpura Henoch–Schönlein purpura is a systemic vasculitis that presents with palpable purpura, abdominal pain, arthritis, and hematuria [1]. The initial clinical symptom of the characteristic purpura makes diagnosis easy. However, the disease is often under-recognized in the 10%–15% of patients in whom gastrointestinal symptoms precede the cutaneous lesion...

Henoch-Schönlein purpura (HSP) is a systemic vasculitis characterized classically by purpura, arthritis and abdominal pain. Epididymitis/orchitis is rarely seen as a complication of HSP. Testicular or scrotal involvement has been reported in children with Henoch-Schonlein purpura and must be distinguished from testicular torsion. We report a case of a 5 year old boy diagnosed with Henoch-Schönl...

Mononeuropathy multiplex is a rare disorder associated with idiopathic thrombocytopenic purpura. Extrinsic compression due to hematoma, intraneural bleed and immune mediated nerve injury are reported mechanisms of neuropathy. We report of a case of a girl with recurrent idiopathic thrombocytopenic purpura with mononeuropathy multiplex, along with a brief review of the mechanism of neuropathies ...

Henoch-Schönlein purpura is an acute, self-limited vasculitis syndrome which shows characteristic skin, joint, renal and gastrointestinal manifestations. It is common in childhood and may also occur in adults with fatal complications such as nephritis and gastrointestinal bleeding. We experienced a case of a 20-year-old woman who presented with palpable purpura and severe arthritis. The histopa...

neonatal purpura fulminans is a rare and life threatening disease that can be inherited or acquired in etiology. it manifests as dic and extensive subcutaneous thrombosis. the condition is often fatal unless there is prompt diagnosis, and judicious therapy. the most important causes of this condition are infections and congenital deficiency of anticoagulant proteins c and s.in the case of pc (p...

conclusions majority of patients had an underlying condition and had various adamts13 activity. the presence of inhibiting antibodies and accompanied complete deficiency of adamts13 activity is an indicator of severity. results we recruited 40 patients (14 males and 26 females) with the mean age of 46.12 ± 17.26 years. the mean activity of adamts13 was 34.58% ± 21.83%. two patients had inhibito...

INTRODUCTION Henoch-Schönlein purpura is a systemic disease with frequent renal involvement, characterized by IgA mesangial deposits. Streptococcal infection can induce an abnormal IgA immune response like Henoch-Schönlein purpura, quite similar to typical acute post-infectious glomerulonephritis. Indeed, hypocomplementemia that is typical of acute glomerulonephritis has also been described in ...