Lateral labial melanocytic nevus or mole has cosmetic value among young or middle aged Iranian ladies particularly those with fair complexion. I describe auto transplantation of a melanocytic nevus from a remote area of the body to lateral labial skin. After selection of a 3-mm nevus, both donor and recipient sites were anesthetized. A punch with a diameter comparable to the diameter of t...

a headache that she had for two years. There was no history of trauma, chronic illness, or exposure to tuberculosis. General and systemic examination revealed no abnormality; she had no neurological deficits. There were no scalp swellings or sinuses. The skull radiograph showed three rounded osteolytic lesions in the right frontal, right parietal, and left frontal regions, with regular punched ...

A 70-year-old Asian man with noninsulin-dependent diabetes presented with a 4-month history of left-sided otitis externa and right-sided facial palsy. Physical examination of the left ear revealed a punched-out ulcerative lesion on the tragus, an edematous and inflamed external auditory canal, and a purulent nonmucoid discharge. Computed tomography of the brain and neck demonstrated a large ret...

Multiple myelomas (MM) are characterized by monoclonal proliferation of immunoglobulin (Ig)-secreting plasma cells. Central nervous system involvement is a rare complication of MM, and it can present as either an intraparenchymal or a leptomeningeal lesion. A 77-year-old woman was transferred from the dementia clinic in July 2012. She had a large heterogeneous signal mass with central necrosis ...

Multiple myeloma is a clonal neoplastic proliferation of terminally differentiated B-lymphocytes involving the skeletal system in a multifocal fashion. Its oral manifestations are less common in the maxilla than in the mandible due to the lower amount of hemopoietic bone marrow in the maxilla. We report the case of a 50-year-old man who presented with a mass in the left maxillary alveolar regio...

Behçet's disease (BD) is a vasculitic disorder of relapsing acute inflammation characterized by recurrent oral ulcers, genital ulcers, uveitis, and skin lesions. The disease also affects other organs, including joints, the nervous system, blood vessels, and gastrointestinal (GI) system may also be involved and the lower GI tract is the mostly involved part, leading to severe morbidity. The freq...

Cold flow is a phenomenon occurring in drug-in-adhesive type of transdermal drug delivery systems (DIA-TDDS) because of the migration of DIA coat beyond the edge. Excessive cold flow can affect their therapeutic effectiveness, make removal of DIA-TDDS difficult from the pouch, and potentially decrease available dose if any drug remains adhered to pouch. There are no compendial or noncompendial ...

us (Dey, 1930 and FitzGerald and Dey, 1931), but the primary lesion, when discovered, is remarkably constant. It seems therefore of interest to record two types, which, whilst they have been previously described, are undoubtedly of great clinical rarity. I. Gumma-like 'primary lesion.?A Lalung woman, aged 20, came to one of our yaws centres, presenting a sore on the ulnar border of the forearm....

Plasmacytoma of the calvarium is very rare, accounting for the 0.7 % of all plasmacytomas [1–5]. The most common locations are the thoracic and lumbar spine (30–40 % of cases). Involvement of the hip, femurs, and ribs is less frequent [6]. Plasmacytoma of the calvarium can be indistinguishable from other lytic lesions, especially metastatic disease. Meningioma, eosinophilic granuloma, and dermo...

Gastric involvement is the least frequent manifestation of Behçet's disease, and effective treatment for it unknown. Here the case of a patient with gastric involvement in Behçet's disease that was markedly improved with adalimumab therapy is presented. A 68-year-old man developed an oral ulcer, erythema, folliculitis, and arthralgia. Behçet's disease was suspected; then, prednisolone and colch...