Modified-Electroconvulsive Therapy (m-ECT) is administered for the treatment of various psychiatric disorders. The Seizure Generalization Hypothesis holds that propagation of the induced seizure throughout the whole brain is essential for the effective ECT intervention. However, we encounter many clinical cases where, due to high thresholds, seizure is not induced by the maximum dose of electri...

Background Secondary hyperparathyroidism is a common complication of chronic kidney disease and is managed using vitamin D replacement therapy. Very few studies have examined the effectiveness of pulse alfacalcidol therapy in comparison to daily oral alfacalcidol therapy in suppressing serum parathyroid hormone (PTH) levels in hemodialysis patients. The aim of this randomized controlled trial w...