During development, the role of the phosphatidylserine receptor (PSR) in the removal of apoptotic cells that have died is poorly understood. We have investigated this role of PSR in developing zebrafish. Programmed cell death began during the shield stage, with dead cells being engulfed by a neighboring cell that showed a normal-looking nucleus and the nuclear condensation multi-micronuclei of ...

The phosphatidylserine receptor (PSR) recognizes a surface marker on apoptotic cells and initiates engulfment. This receptor is important for effective apoptotic cell clearance and maintains normal tissue homeostasis and regulation of the immune response. However, the regulation of PSR expression remains poorly understood. In this study, we determined that interferon regulatory factor-1 (IRF-1)...

We report on 5 years of pulsar observations of the globular cluster NGC5904 (M5). A timing model has been obtained for the two known pulsars, and a deep search for additional faint isolated pulsars has lowered the detection ux limit vefold without further detection. We discuss the details and implications of the phase coherent timing models for PSR B1516+02A and PSR B1516+02B. Of particular int...

Some haematological and rheological features were compared in 27 age and sex matched pairs of patients (15 male, 12 female) with homozygous sickle cell (SS) disease with and without proliferative sickle retinopathy (PSR). Significant haematological differences between the groups were a higher haemoglobin and a lower fetal haemoglobin in PSR positive males and a higher MCHC in PSR positive femal...

We discuss the formation of pulsars with massive companions in eccentric orbits. We demonstrate that the probability for a non-recycled radio pulsar to have a white dwarf as a companion is comparable to that of having an old neutron star as a companion. Special emphasis is given to PSR B1820–11 and PSR B2303+46. Based on population synthesis calculations we argue that PSR B1820–11 and PSR B2303...

This dissertation is a systematic study of artificial neural networks (ANN) applications in power system restoration (PSR). PSR is based on available generation and load to be restored analysis. A literature review showed that the conventional PSR methods, i.e. the pre-established guidelines, the expert systems method, the mathematical programming method and the petri-net method have limitation...

We present an extension of the Dynamics Based Control (DBC) paradigm to environment models based on Predictive State Representations (PSRs). We show an approximate greedy version of the DBC for PSR model, EMT-PSR, and demonstrate how this algorithm can be applied to solve several control problems. We then provide some classifications and requirements of PSR environment models that are necessary...

The paternal sex ratio (PSR) chromosome is a supernumerary chromosome that causes the destruction of the paternal chromosome set in the first mitosis in a fertilized egg. It is known from parasitoid wasps in the genera Nasonia and Trichogramma (Hymenoptera). In these haplodiploids, the egg fertilized by sperm carrying PSR matures as a haploid male that again carries, and is capable of transmitt...

Intragenomic conflict describes a phenomenon in which genetic elements act 'selfishly' to gain a transmission advantage at the expense of the whole genome. A non-essential, selfish B chromosome known as Paternal Sex Ratio (PSR) induces complete elimination of the sperm-derived hereditary material in the jewel wasp Nasonia vitripennis. PSR prevents the paternal chromatin from forming chromosomes...

We report the detection of γ-ray pulsations from the high-magnetic-field rotation-powered pulsar PSR J1119−6127 using data from the Fermi Large Area Telescope. The γ-ray light curve of PSR J1119−6127 shows a single, wide peak offset from the radio peak by 0.43± 0.02 in phase. Spectral analysis suggests a power law of index 1.0± 0.3 −0.2 with an energy cut-off at 0.8± 0.2 +2.0 −0.5GeV. The first...