Collagenous gastritis is a rare cause of heartburn in adults. Histopathological examination gastric mucosal biopsy from the stomach shows submucosal collagen deposition. The pathophysiologic mechanism unknown, and collagenous cases have been associated with certain drugs, such as olmesartan non-steroidal anti-inflammatory medical conditions, common variable immunodeficiency, primary IgM deficie...

Acrodermatitis continua of Hallopeau (ACH) is a rare form of pustular psoriasis, mainly affecting distal phalanges of hands and feet. Many therapeutic options exist; however, it tends to be resistant to treatment. We report a 26-year-old man presented with a very severe psoriatic arthritis associated with ACH. Although this patient was resistant to a first line treatment (glucocorticoids and me...

Methotrexate nodulosis in conditions other than rheumatoid arthritis is very rare. It has been reported in a patient with systemic lupus erythematosus and Jaccoud’s arthropathy [4], a patient with juvenile arthritis who was rheumatoid factor negative [5], and a patient with psoriatic arthritis and negative rheumatoid factor [6]. Only the patient with juvenile arthritis had pulmonary nodules. Ho...

CASE HISTORY. A 19-year-old student nurse presented with a four month history of pain and stiffness in her knees, ankles and elbows following a brief 'flu-like illness. Wrist and elbow movements were limited, with bilateral knee effusions and flexion deformities of approximately 100. Evidence of psoriasis was limited to areas of hyperkeratosis on the elbows, and a few nail pits; there was a pos...

Histocompatibility typing was carried out in 74 patients with psoriasis and an inflammatory arthropathy. In 40 patients with peripheral arthropathy characterized by distal interphalangeal joint involvement, 13 (32-5%) were HLA-B27 positive, significantly higher than the control frequency (P = 5-8 X 10 (-6). 26 of the 40 patients did not have ankylosing spondylitis or radiological sacroiliitis a...

This article reviews recent advances in psoriatic arthritis (PsA) over the past several years with emphasis on early diagnosis, better understanding of pathogenesis, and new therapeutic approaches. Early diagnosis is important, since people who present late do not fare as well. There are a number of clinical, laboratory, and ultrasound features that can help identify patients destined to develo...

The clinical significance of cytoplasmic inclusions(CPI) in synovial fluid(SF) examination was evaluated. We examined SF specimens collected from major rheumatology clinics in the Philadelphia area during the period of January to December 1995. Among 759 patients in the initial study group, 419 cases with established diagnoses and full synovial analyses were included. Their diagnoses and SF ana...

Patients: 72 073 adults ≥ 40 years of age (mean age 65 y, 71% men) who had an incident diagnosis of gout. The control group comprised 358 342 adults without gout, matched for age, sex, date of study entry, and enrollment year. Exclusion criteria were history of septic arthritis, gout, osteoarthritis, rheumatoid arthritis, or other inflammatory rheumatic condition (seronegative spondyloarthropat...