conclusions using tzpsad as an adjunct to psa may improve the specificity of psa in the diagnosis of pca and decrease the number of unnecessary prostatic biopsies in iranian men with serum psa level < 20 ng/ml. results among 1120 men who were eligible for enrolment, prostate cancer was detected in 265 patients. mean serum psa levels were 9.7 ± 4.3 ng/ml and 8.5 ± 3.7 ng/ml in patients with and ...

background: prostate specific antigen (psa) is an important laboratory marker for diagnosis of prostatic cancer. thus, development of diagnostic tools specific for psa plays an important role in screening, monitoring and early diagnosis of prostate cancer. in this paper, the production and characterization of a panel of murine monoclonal antibodies (mabs) against psa have been presented.  metho...

there are emerging data on novel tumor markers such as matrix metalloproteinase-2 (mmp-2 or gelatinase-a), which play a key role in tissue invasion and metastasis. we designed an investigation to assess the usefulness of mmp-2 activity as compared to prostate specific antigen (psa) in cancer staging process. we have analyzed the circulating form of mmp-2 in serum samples of patients suffering f...

abstract   background: regarding the variety of tests present for detecting and also screening prostate cancer and also bearing in mind the advantages and disadvantages of these tests we decided to re-evaluate these tests (total prostate specific antigen and all of its modifications) in detecting prostate cancer in men with intermediate serum psalevels.   methods: following a cross sectional st...

conclusions regular resistance training and prostatic massage can improve proinflammatory markers and psa levels in men with pc. results in the resistance training group, il-10 levels significantly increased after four (p = 0.055) and eight weeks (p = 0.000). four and eight weeks of resistance training showed a significant reduction in psa, crp, il-6, and tnf-α levels (p < 0.05). patients of ma...