Background: Presence of discordance between the Gleason score on needle biopsy and the score of radical prostatectomy specimen is common and universal. In this study, we determined the accuracy of Gleason grading of biopsies in predicting histological grading of radical prostatectomy specimens and the degree of overgrading and undergrading of prostatic adenocarcinoma i...

Introduction The recent symbiosis between robotics and medical science has made a rapid development, particularly in imaging and interventions. Different imaging modalities provide feedback to interventional devices which are crucial in precise positioning tasks such as needle insertion, biopsy interventions and catheter placement. Prostate cancer is the most frequently diagnosed form of noncut...

Prostate biopsy is the only examination that enables urologists to diagnose prostate cancer. It consists in taking off samples of the gland using a biopsy needle that slides in a needle-guide rigidly attached to a transrectal ultrasound probe. In clinical routine twelve systematic biopsies are distributed in the prostate volume and additional targeted samples can be taken in a given zone of int...

PURPOSE Biopsy Gleason score, serum prostate specific antigen (PSA) levels, and clinical stage are known to be independent predictors of adverse pathological features and biochemical failure after radical prostatectomy. We determine whether various prostate needle biopsy parameters were predictive of either adverse pathological findings or disease recurrence after radical prostatectomy. MATER...

This paper reports a novel remotely actuated device for transrectal prostate biopsy, designed for use in a conventional high-field MRI scanner. The device provides three-dimensional MRI guided biopsy needle placement with sub-millimeter accuracy under physician control. Its compact size enables use in both closed and open configuration MRI scanners. Preliminary in-vivo canine experiments demons...

  Background and Objective: Non-specific granulomatous prostatitis is an uncommon diffuse inflammatory condition of the prostate. It is important because it may be mistaken for prostatic carcinoma. The aim of the study was to determine the prevalence of non-specific granulomatous prostatitis (NSGP) and comparing the results of transrectal ultrasonography, serum prostate specific antigen (PSA) ...

AIM To investigate the relationship of serum prostate-specific antigen (PSA) levels with outcomes of prostate needle biopsy in men 50 or more years old. METHODS We measured serum PSA levels in 1472 healthy men 50 or more years old. Men who had serum PSA values 4.0ng/mL or higher underwent digital rectal examination. If there were either an elevated PSA level (≥4ng/mL) or abnormal digital rect...

background the aim of the present study was to compare two analgesic techniques for transrectal ultrasound (trus)-guided biopsy: diclofenac patch versus periprostatic nerve block with 1% lidocaine. objectives to study the efficacy of and compare diclofenac patch and periprostatic nerve block as analgesia in trus-guided prostate needle biopsy. patients and methods in total, 60 patients were pros...

Neutrophil-to-lymphocyte ratio (NLR), a simple marker of systemic inflammatory response, has been demonstrated as an independent prognosticator for some solid malignancies, including prostate cancer. In the present study, we evaluated the role of NLR in men who underwent prostate needle biopsy for their initial diagnosis of prostatic carcinoma. Both complete blood counts and free/total (F/T) pr...

Clinical diagnosis of prostate cancer is most often done by transrectal ultrasound-guided needle biopsy. Because of the low resolution of ultrasound, however, the urologist cannot usually distinguish between cancerous and healthy tissue. Therefore, most biopsies follow standard procedures (known as “protocols”) based on long-term physician experience. Recent studies indicate that these protocol...