Purpose We illustrate the importance of small quantities (<10 mol%) of polar phospholipids on the surface-active behavior of meibum-like lipid compositions. Methods Artificial meibum-like lipid mixture containing cholesteryl and wax esters was mixed with differing amounts of phosphatidylcholine (PC). The surface activity of these mixtures was investigated at the air-water interface by recordi...

(Na+ + K+)-ATPase from kidney outer medulla was incorporated into tightly-sealed, single-shelled lipid vesicles by a detergent-dialysis procedure. The rate of ATP-driven potassium extrusion from vesicles formed from different phosphatidylcholines (PC) was measured optically, using a voltage-sensitive dye in the presence of valinomycin. High transport rates were observed for di(18:1)PC, di(20:1)...

Purpose Digital breast tomosynthesis (DBT) is a limited-angle tomographic imaging modality that can be used for cancer screening in conjunction with full-field digital mammography (FFDM) or synthetic (SM). Currently, there are five commercial DBT systems have been approved by the U.S. FDA screening, all varying greatly design and protocol. Because different technical specifications, need quanti...

Graupel mixing ratio over Bulgaria for the warm half year of 2021 based on AROME-BG numerical weather prediction (NWP) model, is evaluated and connected lightning data detected by ATDnet location network. Lightning forecasted graupel ratios were considered resolutions 5×5 km 10×10 with flash rate one three hours, as well a daily base using upscaling neighborhood method. Two model runs are – at ...

BACKGROUND Phosphatidylcholine (PC) produced via the S-adenosylmethionine-dependent phosphatidylethanolamine (PE) N-methyltransferase (PEMT) pathway is enriched with docosahexaenoic acid (DHA). DHA plays a critical role in fetal development and is linked to health endpoints in adulthood. It is unknown whether choline, which can serve as a source of S-adenosylmethionine methyl groups, influences...

China is experiencing a syphilis epidemic of enormous proportions. The regions most heavily affected by syphilis correspond to regions where sexually transmitted HIV infection is also a major public health threat. Many high-risk patients in China fail to receive routine syphilis screening. This missed public health opportunity stems from both a failure of many high-risk individuals to seek clin...

Exo-endocytotic turnover of synaptic vesicles (SVs) at synapses between hippocampal neurons in culture was examined by electron microscopy (EM). We carried out photoconversion (PC) of the fluorescent endocytotic marker FM 1-43 by using 3,3'-diaminobenzidine to convert the dye signal into an electron-dense product. Electron-dense products were located almost exclusively in SVs, whose densities w...

BACKGROUND Adequate estimation of the potential benefits of 'adjuvant' hyperthermia and intraperitoneal chemotherapy (HIPEC) in T4 patients through assessment of the burden of peritoneal carcinomatosis (PC) in T4 tumors and the risk of PC as the only metastatic site. PATIENTS AND METHODS Analysis of prospectively collected data on patients who underwent surgery for colon cancer (Jan 2004-Jan ...

Application of the Next generation sequencing (NGS) technology has demonstrated that most tumor samples exhibit intra-tumor heterogeneity. Here we proposed SAPPH (Somatic Aberrations Prediction for Paired Heterogeneous tumor samples), as a new method for estimating tumor somatic copy number aberrations as well as inferring tumor subclone proportions from heterogeneous tumor sequencing data. Thi...

The security level of the achievability scheme for Wyner’s wiretap channel model is examined from the perspective of the probability of correct decoding, Pc, at the wiretap channel decoder. In particular, for finite–alphabet memoryless channels, the exact random coding exponent of Pc is derived as a function of the total coding rate R1 and the rate of each sub–code R2. Two different representat...