نتایج جستجو برای: propionic acidemia

تعداد نتایج: 4552  

2015
Cigdem Seher Kasapkara Murat Kangin Banu Oflaz Ozmen Mehmet Nuri Ozbek Remezan Demir Mustafa Karatas Leyla Tumer Fatih Suhey Ezgu Alev Hasanoglu

1Department of Pediatric Metabolism and Nutrition, Diyarbakir Children’s Hospital, Diyarbakir, Turkey 2Pediatric Intensive Care Unit, Diyarbakir Children’s Hospital, Diyarbakir, Turkey 3Department of Pediatric Hematology and Oncology, Diyarbakir Children’s Hospital, Diyarbakir, Turkey 4Department of Pediatric Endocrinology, Diyarbakır Children’s Hospital, Diyarbakir, Turkey 5Department of Pedia...

2013
Ali M. Al-Asmari AbdulKarim S. Al-Makadma

One of the most common recessively inherited organic acidemias is the Propionic Acidosis (PA) which results from Propionyle-CoA Carboxylase (PCC) enzyme deficiency that is necessary for the catabolism of the branched chain Amino Acids and other metabolites. Classically this disease presented with high anion gap metabolic acidosis with its clinical consequences. We report 4 patients who presente...

Journal: :The British journal of ophthalmology 2016
Lidia Martinez Alvarez Elisabeth Jameson Neil R A Parry Chris Lloyd Jane L Ashworth

BACKGROUND Methylmalonic acidemia (MMA) and propionic acidemia (PA) are rare hereditary disorders of protein metabolism, manifesting early in life with ketoacidosis and encephalopathy and often resulting in chronic complications. Optic neuropathy (ON) has been increasingly recognised in both conditions, mostly through isolated case reports or small cases series. We here report the clinical feat...

Journal: :Molecular genetics and metabolism 2012
Kimberly A Chapman Andrea Gropman Erin MacLeod Kathy Stagni Marshall L Summar Keiko Ueda Nicholas Ah Mew Jill Franks Eddie Island Dietrich Matern Loren Pena Brittany Smith V Reid Sutton Tiina Urv Charles Venditti Anupam Chakrapani

Propionic acidemia or aciduria is an intoxication-type disorder of organic metabolism. Patients deteriorate in times of increased metabolic demand and subsequent catabolism. Metabolic decompensation can manifest with lethargy, vomiting, coma and death if not appropriately treated. On January 28-30, 2011 in Washington, D.C., Children's National Medical Center hosted a group of clinicians, scient...

Journal: :Journal of Human Genetics 2006

Journal: :Molecular Genetics and Metabolism 2016

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