نتایج جستجو برای: prolonged release
تعداد نتایج: 297804 فیلتر نتایج به سال:
Recent experience has prompted the US FDA to consider whether ethanol ingestion may modify the release characteristics of prolonged-release formulations, where dose dumping may be an issue for patient safety. The influence of ethanol on the in vitro release of opioid drugs from some prolonged-release formulations utilizing different release technologies was examined. Results indicated that the ...
This study was done to evaluate transvaginal ultrasonographic measurement of cervical length at 20 to 24 weeks and 37 weeks as a predictor of prolonged pregnancy (defined as a pregnancy that extended beyond 41+2 weeks of gestation [289 days]) in nulliparous women. This prospective observational study enrolled 149 consecutive nulliparous women with singleton gestation at 37 weeks. Cervical lengt...
Scant scientific attention has been given to the abundance and distribution of marine biota in the face of the lower sea level, and steeper latitudinal gradient in climate, during the ice-age conditions that have dominated the past million years. Here we examine the glacial persistence of Atlantic cod (Gadus morhua) populations using two ecological-niche-models (ENM) and the first broad synthes...
UNLABELLED DIAMOND: multicenter, 24-week, randomized trial investigating the effect of different once-daily, prolonged-release tacrolimus dosing regimens on renal function after de novo liver transplantation. Arm 1: prolonged-release tacrolimus (initial dose 0.2mg/kg/day); Arm 2: prolonged-release tacrolimus (0.15-0.175mg/kg/day) plus basiliximab; Arm 3: prolonged-release tacrolimus (0.2mg/kg/d...
preparation and characterization of thermoresponsive in-situ forming poloxamer hydrogel for controlled release of nile red-loaded solid lipid nanoparticles. nanoparticles (nps) are cleared rapidly from systemic circulation and do not provide sustained action in most cases. to solve this problem, this investigation introduces an erodible in-situ forming gel system as potential vehicles for prolo...
BACKGROUND Diabetes is a major comorbidity in insomnia patients. The efficacy and safety of prolonged-release melatonin 2 mg in the treatment of glucose, lipid metabolism, and sleep was studied in 36 type 2 diabetic patients with insomnia (11 men, 25 women, age 46-77 years). METHODS In a randomized, double-blind, crossover study, the subjects were treated for 3 weeks (period 1) with prolonged...
hypertension crisis is one of the main health problems and its effective treatment is of high importance. for this purpose, fast-disintegrating and sustained release formulations of captopril, as a drug of choice, were prepared using conventional mucoadhesive polymers hydroxypropyl methylcellulose (hpmc), sodium carboxymethyl cellulose (na-cmc), hydroxypropyl cellulose (hpc), carbopol 934 (cp93...
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