autism is a severe neurodevelopmental disorder that characterized by abnormal bilateral social interaction, deficiency in verbal and nonverbal communication, restricted interests and repetitive behaviors .autism caused by the inappropriate immune response which released several cytokines. one of the most important and main causes of autism is a defect in, the formation of the neuronal synaptic ...

a central role for t cells and their cytokines in the pathogenesis of psoriasis has been proposed; however, there are controversies over the details of this issue. the goal of this study is to summarise currently available data on the importance of t cells in psoriasis pathogenesis. a  systematic  review  of  the  english  medical  literature  was  conducted  by  searching pubmed, embase, isi w...

background: preeclampsia is a major cause of mortality and morbidity and is also a leading cause of preterm birth and intrauterine growth retardation. several studies have reported abnormal levels of cytokines in women with preeclampsia. objectives: to detect serum levels of various cytokines in pregnant women with and without preeclampsia in the third trimester of pregnancy. methods: thirty pa...

traumatic brain injury (tbi) is a global health concern that typically causes emotional disturbances and cognitive dysfunction. it elicits a complex secondary injury response, with neuroinflammation as a crucial central component. secondary pathologies following tbi may be associated with chronic neurodegenerative disorders and an enhanced likelihood of developing dementia-like disease in later...

background: major depression disorder (mdd) is a common disorder with preva-lence of 15% among men and up to 25% among women. in recent years the association of immune system alterations and mdd has been investigated. assessments of immu-nologic and inflammatory responses in these patients enhance our knowledge of the eti-ology and pathogenesis of this disease. objective: to investigate the cha...

introduction: boron possesses widespread properties and is important for human and animal nutrition. since boron is rapidly bioavailable, the objective of the present study was to determine whether acute (hourly or daily), and weekly supplementationcould have any significant biological effects on the synthesis of steroids as well as inflammatory biomarkers. methods: eight male volunteers partic...

background: to evaluate vdr gene variation and its interaction with immune regulatory molecules in osteoporosis. methods: totally 205 pre and postmenopausal women were recruited in the study. after an overnight fast, peripheral blood was taken and centrifuged to sprat serum for measurement of serum parathyroid hormone, 25 hydroxyvitamin d, osteocal­cin and cross laps. the fok i polymorphism in ...