Purpose. To evaluate the effect of corneal crosslinking in progressive keratoconus by applying in vivo corneal visualization Scheimpflug technology. Design. Longitudinal retrospective study. Subjects and Controls. Seventeen eyes of patients treated with corneal crosslinking for progressive keratoconus. Methods. Corneal visualization Scheimpflug technology analyses (research software version 6.0...

Keratoconus is a degenerative disorder with progressive stromal thinning and transformation of the normal corneal architecture towards ectasia that results in decreased vision due to irregular astigmatism and irreversible tissue scarring. The pathogenesis of keratoconus still remains unclear. Hypotheses that this condition has an inflammatory etiopathogenetic component apart from the genetic an...

Corneal hysteresis (CH) is a parameter which measures the viscoelastic behaviour of the cornea, indicating its biomechanical integrity1. Some clinical conditions such as keratoconus, Fuchs corneal dystrophy, high myopia, glaucoma and corneal refractive surgery, may induce changes in corneal biomechanical properties, leading to a decrease in CH2-6. Astigmatism, a refractive error related to corn...

PURPOSE To evaluate the long-term clinical effectiveness and safety of corneal collagen cross-linking (CXL) in progressive keratoconus compared with untreated contralateral eyes. METHODS In this retrospective study, nine eyes of nine patients with progressive keratoconus who received CXL (treatment group) and nine untreated contralateral eyes with keratoconus (control group) were included. Al...

To compare the efficacy of epithelium-off corneal collagen crosslinking (CXL) with transepithelial CXL in patients progressive keratoconus a follow-up 3 years, taking into account patients’ age and location ectasia. In this prospective study participated 64 eyes were included long-term study, which 31 treated by 33 CXL. All 36 months evaluated for visual variables (corrected distance acuity (CD...

Progressive hemifacial atrophy (Parry-Romberg syndrome, PHA) is characterised by slowly progressive atrophy, usually involving one side of the face, and may be associated with ocular manifestations which include enophthalmos, restrictive strabismus and hypotony. We report a case of keratoconus seen in a patient with PHA after obtaining approval from our Institutional Review Board. We are unawar...

Francois Malecaze MD commenced the session with an update on current research into the genetics of keratoconus. Dr Malecaze noted that forme fruste keratoconus is one of the major causes of post-LASIK corneal ectasia and the condition may be due to genetic factors in the majority of cases. Identification of the gene or genes responsible for keratoconus might lead to the development of blood tes...

OBJECTIVE To determine the Efficacy of Corneal Crosslinkage (CXL), using Corneal Topography, in eyes with progressive Keratoconus. METHODS This randomized control trial was conducted at Armed Forces Institute of Ophthalmology, Rawalpindi, Pakistan from October 2013 to April 2014. A total of 60 eyes of 30 patients were included who presented with bilateral progressive Keratoconus. Each eye of ...

K eratoconus (OMIM148300) is a bilateral, non-inflammatory, slowly progressive, corneal ectasia that is a major cause of corneal transplant. Characteristically, the cornea becomes thin and conical, with myopia and irregular astigmatism that leads to vision impairment. The incidence of keratoconus is between 50 and 230 per 100 000, with remarkable differences between ethnic groups. Although the ...