نتایج جستجو برای: programmed cell death 1 receptor

تعداد نتایج: 4393069  

Journal: :iranian journal of basic medical sciences 0
seyed hadi mousavi department of pharmacology and pharmacological research centre of medicinal plants, school of medicine, mashhad university of medical sciences, mashhad, iran medical toxicology research center, mashhad university of medical sciences, mashhad, iran zahra tayarani-najaran department of pharmacology and pharmacological research centre of medicinal plants, school of medicine, mashhad university of medical sciences, mashhad, iran peter hersey immunology and oncology unit, newcastle mater hospital, newcastle, new south wales, australia

apoptosis or programmed cell death is a gene regulated phenomenon which is important in both physiological and pathological conditions. it is characterized by distinct morphological features including chromatin condensation, cell and nuclear shrinkage, membrane blebbing and oligonucleosomal dna fragmentation. although, two major apoptotic pathways including 1) the death receptor (extrinsic) and...

Journal: :European Journal of Immunology 2021

Immunogenic cancer therapies, including radiation and hypomethylating agents, such as 5-azacytidine, rely on tumor cell-intrinsic activation of the RNA receptor RIG-I for their synergism with immune checkpoint inhibitors. Possible ligands are small nuclear (snRNA) endogenous retroviral elements (ERV) leaking from nucleus during programmed cell death.

Peter Hersey Seyed Hadi Mousavi, Zahra Tayarani-Najaran

Apoptosis or programmed cell death is a gene regulated phenomenon which is important in both physiological and pathological conditions. It is characterized by distinct morphological features including chromatin condensation, cell and nuclear shrinkage, membrane blebbing and oligonucleosomal DNA fragmentation. Although, two major apoptotic pathways including 1) the death receptor (extrinsic) and...

Central ossifying fibroma is a benign, slow-growing tumor of mesenchymal origin with a predilection for the mandibular premolar and molar areas. The immunophenotype of T cells involved in the antitumor response against this benign tumor is unknown. In this case report, we described a case of a 48-year-old woman presenting with a very large recurrent ossifying fibroma in the mandible, which was ...

Journal: :Skin 2023

The development of immune checkpoint inhibitors such as programmed cell-death receptor 1 (PD-1) antagonists has rapidly advanced chemotherapy within the last several decades. PD-1 targeted immunotherapy drugs like pembrolizumab, ipilimumab, nivolumab, and durvalumab have known associations with immune-mediated dermatological reactions. We report a case in which an elderly male experienced segme...

Journal: :gastroenterology and hepatology from bed to bench 0
florence folmer marcel jaspars mario dicato marc diederich

programmed cell death, which can be classified into apoptosis, autophagy, and oncosis, based on the cellular signalling pathways involved in the process, plays a critical role in cellular house-keeping. aberrant cell death regulation leads to body malformations, as well as to numerous diseases. here, we describe the effects of cytototoxins isolated from marine organisms on the various programme...

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