BACKGROUND A combination of taxanes and cisplatin have shown modest activity as second-line chemotherapy in breast cancer patients who have been exposed to anthracyclines. The purpose of this study was to retrospectively assess whether HER2 is associated with clinical sensitivity or with prognostic significance in breast cancer patient groups who had received chemotherapy with taxanes and cispl...

BACKGROUND: In mare, different methods of earlier cyclicity induction and hastening first ovulation of the year have been reported. OBJECTIVES: The goal of present study was to investigate the effect of progesterone (Cue-mate®) on synchronization and acceleration the first ovulation of the year in winter anestrous mares under artificial lighting system. METHODS: After detection of anestrus mare...

In the previous studies a hypothesis was developed from the results by using trivariate Weibull model that the increase in leptin concentrations during the second half of the menstrual cycle may be related to changes in the steroidal milieu during the pre ovulatory period and the luteal phase. The present study was undertaken to test this hypothesis further by examining the effect of treatment ...

In the previous studies a hypothesis was developed from the results that the increase in leptin concentrations during the second half of the menstrual cycle may be related to changes in the steroidal milieu during the preovulatory period and the luteal phase. The present study was undertaken to test this hypothesis further by examining the effect of treatment with oestradiol and progesterone on...

Cumulative pregnancy rate has been significantly increased since frozen-thawed embryo transfer was applied in ART cycles. This method has become an essential part of IVF/ICSI treatment. Luteal phase support has been proven to be associated with higher rate of live birth rate. Human chorionic gonadotropin (HCG), and progestrone have been successfully used for luteal phase support in ovarian stim...

Breast cancer is the second leading cause of cancer death in women. Serum biomarkers such as cancer antigen 15-3 (CA15-3), cancer antigen 125 (CA125), and carcinoembryonic antigen (CEA) can be used as diagnostic and prognostic factors and can also provide valuable information during follow-up. However, serum protein biomarkers show limited diagnostic sensitivity and specificity in stand-alone a...

RATIONALE Luminal subtype breast cancer, accounting for 70 to 80% of all breast cancers, has been reported to be associated with good prognosis. However, for the patients with large mass or worse mass position, omental flap transplantation may provide a new option for breast reconstruction. PATIENT CONCERNS Ten patients (6 luminal B1, 2 luminal B2, 2 luminal A), were enrolled into the study, ...

The aim of this trial was to evaluate the effectiveness (fertility and lambing) of priming with a single injection of progesterone plus PMSG in anovulatory lactating Sarda ewes subjected to the ram effect (RE) in spring. Thirty ewes (P4 group) were i.m. injected with 30 mg progesterone and 500 IU PMSG 36 h before ram introduction (d 0). This treatment was compared to a 12-day treatment with flu...

Background: Systemic Lupus Eyrythematosus (SLE) is an autoimmune disease charac-terized by antibodies to nuclear antigens, particularly anti-dsDNA. Imbalance between production and destruction of immune cells causes cytopenia. Sex hormones have im-munomodulatory effects; estrogen increases the production of autoantibodies in SLE prone NZB/NZW mice. Objective: To investigate the relationship bet...

to evaluate the effectiveness of conjugated estrogen (premarin) and progesterone in twenty-one postmenopausal women who had been menopause one year, we tested during a 6-month period the serum lipoprotein levels in subjects who offered by premarin in dosage of 0.625 milligram for days 1 to 25 and oral medroxy progestrone acetste for days 15 to 25 of a 30-day cycle. twenty-one subjects completed...