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the development and implementation of non-animal alternative tools in education and training are often the result of an evaluation process where the replacement of harmful animal use with humane, innovative methods reflects a range of pedagogical, ethical, environmental and economic considerations. InterNICHe helps realise its vision of a fully humane education by developing, promoting and impl...

This paper proposes a quadratic programming method (QPM) for ranking alternatives based on multiplicative preference relations (MPRs) and fuzzy preference relations (FPRs). The proposed QPM can be used for deriving a ranking from either a MPR or a FPR, or a group of MPRs, or a group of FPRs, or their mixtures. The proposed approach is tested and examined with two numerical examples, and compara...

Macroeconomic forecasts are used extensively in industry and government The historical accuracy of US and UK forecasts are examined in the light of different approaches to evaluating macro forecasts. Issues discussed include the comparative accuracy of macroeconometric models compared to their time series alternatives, whether the forecasting record has improved over time, the rationality of ma...

In an extreme event or major disaster, very often there are both alternative actions that might be considered and far more requests for actions than can be executed immediately. The relative desirability of each option for action could be a collaborative expression of a significant number of emergency managers and experts trying to manage the most desirable alternatives at any given time, in re...

There has long been interest in understanding the genetic basis of human adaptation. To what extent are phenotypic differences among human populations driven by natural selection? With the recent arrival of large genome-wide data sets on human variation, there is now unprecedented opportunity for progress on this type of question. Several lines of evidence argue for an important role of positiv...

There is an urgent need to develop data integration and testing strategy frameworks allowing interpretation of results from animal alternative test batteries. To this end, we developed a Bayesian Network Integrated Testing Strategy (BN ITS) with the goal to estimate skin sensitization hazard as a test case of previously developed concepts (Jaworska et al., 2010). The BN ITS combines in silico, ...

We propose an adjunction-based analysis of comparative (and similar) constructions that captures the morphological and semantic relation between comparative heads (e.g., -er, as) and comparative clauses (e.g., those headed by than or as). Primarily motivating this proposal are the syntactic similarities that we observe between comparative constructions and other adjunction structures in grammar...