نتایج جستجو برای: proadrenomedullin n terminal 20 peptide

تعداد نتایج: 1704817  

Journal: :Microscopy research and technique 2002
Alfonso Calvo Ibane Abasolo Nuria Jiménez Zhou Wang Luis Montuenga

There is increasing evidence for the important role played by regulatory peptides in the physiology of the normal and neoplastic prostate. Adrenomedullin (AM) and pro-adrenomedullin N-terminal 20 peptide (PAMP) are recently discovered regulatory peptides widely expressed in the normal prostate and in prostate carcinoma. AM is produced in secretory, stroma, and endothelial cells and in neurons o...

1998
Manjula Mahata Sushil K. Mahata Robert J. Parmer Daniel T. O’Connor

Proadrenomedullin N-terminal 20 peptide (PAMP-[1-20]; ARLDVASEFRKKWNKWALSR-amide) is a potent hypotensive and catecholamine release–inhibitory peptide released from chromaffin cells. We studied the mechanism of PAMP action and how its function is linked to structure. We tested human PAMP-[1-20] on catecholamine secretion in PC12 pheochromocytoma cells and found it to be a potent, dose-dependent...

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