purpose: this study evaluated the effect of donor and eye bank characteristics on graft rating and clinical outcomes after penetrating keratoplasty (pk) in keratoconus-affected patients. methods: a total of 252 consecutive keratoconic eyes that underwent pk were reviewed in this retrospective interventional case series. donor data included age and sex, cause of death, death-to-preservation time...

BACKGROUND Bacterial contamination during cold organ preservation occurs without major complications. However, with organ preservation steering toward (sub)normothermic temperatures, bacterial contamination may be detrimental with limited evidence to support the choice of antibiotic. METHODS This study aimed to determine the effective antibiotic prophylaxis for (sub)normothermic preservation ...

We quantitatively studied the role of periosteum and bone marrow-endosteum during lengthening in 18 growing rabbits, comparing four surgical procedures: 1) periosteum and bone marrow preservation, 2) periosteum preservation, bone marrow destruction, 3) periosteum destruction, bone marrow preservation, 4) periosteum and bone marrow destruction. An external fixator was set on one femur, the other...

Gas hydrates could show an unexpected high stability at conditions out of thermodynamic equilibrium, which is called the self-preservation effect. The mechanism of the effect for methane hydrates is here investigated via molecular dynamics simulations, in which an NVT/E method is introduced to represent different levels of heat transfer resistance. Our simulations suggest a coupling between the...

Adequate storage of polymorphonuclear leukocytes would allow an easier in vitro study of their structure and their functions, an easier study of polymorphonuclear leukocyte diseases (e.g. chronic granulomatous disease) and an easier use of polymorphonuclear leukocytes as a clinical tool (e.g. for localizing infections). Unfortunately, polymorphonuclear leukocytes are nearly impossible to preser...

Distributed digital preservation is a maturing and appealing solution to the pressing problem of ensuring the survivability of digital content. Like all other digital preservation efforts, distributed digital preservation solutions must communicate trust to their Designated Communities as they continue to mature. The following paper discusses the importance of establishing this trust, retraces ...