results serum estradiol levels tended to have a negative correlation with homeostasis model assessment of insulin resistance (homa-ir) in premenopausal women but not in postmenopausal women. on the other hand, free testosterone levels tended to have a positive correlation with homa-ir in postmenopausal women but not in premenopausal women. serum shbg levels showed significant negative correlati...

Morbidity and mortality associated with osteoporosis continues to be high in India primarily due to late diagnosis. This study aims to find association of age, body mass index (BMI) and menopausal status with bone mineral density (BMD); and confirm if these variables are predictors of low BMD in premenopausal and postmenopausal women. This cross sectional study was conducted on 350 women aged 3...

BACKGROUND AND PURPOSE Hemodynamic factors seem to play an important role in the pathogenesis of cerebral ischemic events. The aim of this study was to evaluate whether changes in cerebrovascular reactivity occur in women after menopause. METHODS Using transcranial Doppler ultrasonography, we studied the changes of flow velocity after hypercapnia in the middle cerebral arteries of 45 healthy ...

Evidence has long demonstrated that premenopausal women obtain the greatest benefit from adjuvant chemotherapy overall, with risk reduction increasing with decreasing age. The chemoendocrine effect of chemotherapy has only more recently been documented as impacting on outcomes for women with hormone receptor-positive breast cancer, and recent data have elucidated the optimal strategies for mani...

The aim of present study was comparison of cardiac autonomic status during different phases of reproductive life in women - in premenopausal women between proliferative and secretory phase, in postmenopausal women and in postmenopausal women receiving hormone replacement therapy (HRT). The study included 30 premenopausal women (Group 1) who were assessed in both proliferative (Group 1A) and sec...

Plasma estrogen and progesterone levels were deter mined in 77 premenopausal and 137 menopausa! women at the same time that estradiol receptor (ER) and proges terone receptor (PGR) assays were carried out on their breast cancers. The frequency of ER and PGR is approxi mately the same in premenopausal and postmenopausal women, but the ER content is much higher in postmeno pausal women. Although ...

Bone mineral density (BMD) achieved during young adulthood (peak BMD) is one of the major determinants of osteoporotic fracture in later life. Genetic variants associated with BMD have been identified by three recent genome-wide association studies. The most significant single-nucleotide polymorphisms (SNPs) from these studies were genotyped to test whether they were associated with peak BMD in...

BACKGROUND There is sufficient evidence supporting a relationship between increased body mass index (BMI) and an increased risk for breast cancer among postmenopausal women. However, most studies have found a decreased risk for premenopausal breast cancer. This study was conducted to find out the different effects of BMI on the risk of breast cancer among premenopausal and postmenopausal women,...

Background: To study the clinical presentation and coronary angiographic profile in premenopausal women with acute coronary syndrome 2. To compare with the clinical presentation and coronary angiographic profile in postmenopausal women with acute coronary syndrome Method: 43 Patients with Acute Coronary Syndrome admitted in department of cardiology King George Hospital Visakhapatnam , who under...