We evaluated the prognostic value of serum endostatin and vascular endothelial growth factor (VEGF) for diagnosis of pre-eclampsia. We determined VEGF and endostatin levels in the sera of 20 healthy, non-pregnant women and 64 pregnant women: 20 healthy, 20 with mild pre-eclampsia and 24 with severe pre-eclampsia. Serum levels of these factors in non-pregnant women were similar to those in healt...

background preeclampsia is one of the leading causes of maternal mortality and morbidity. its prevalence varies between 10-25% among high-risk pregnant patients. objectives the aim of this study was to determine whether treatment with acetylsalicylic acid (asa) reduces the incidence of preeclampsia among pregnant women with abnormal uterine artery flow. patients and methods in this double-blind...

OBJECTIVE To evaluate whether first trimester maternal serum PP13 can predict pre-eclampsia among women with a priori high risk. METHOD This was a nested case-control study. Women less than 14 weeks' gestation at increased risk of developing pre-eclampsia were recruited. Venous blood samples were assayed for PP13 using enzyme-linked immunosorbent assay. PP13 multiples of median (MoM) were cal...

Introduction: Pre-eclampsia is one of the complexities of maternal and neonatal health. There are several similarities between pre-eclampsia and atherosclerosis. The relation between chronic Chlamydia pneumoniae infections with atherosclerosis has been shown previously. This study has been done to determine the connection between pathogenesis and onset time of pre-eclampsia and chronic Chlamydi...

OBJECTIVE To investigate whether pre-eclampsia is more common in first pregnancies solely because fewer affected women, who presumably have a higher risk of recurrence, go on to have subsequent pregnancies. DESIGN Prospective cohort study. SETTING Swedish Medical Birth Register. PARTICIPANTS 763 795 primiparous mothers who had their first births in Sweden, 1987-2004. MAIN OUTCOME MEASUR...

background: leptin is a protein product of obesity gene and is synthesized mainly by adipose tissue. objective: the aim of this study was to determine maternal and neonatal serum leptin levels in term preeclamptic and normal pregnancies. materials and methods: this cross sectional study was performed on 37 preeclamptic and 40 normotensive term pregnant women without other disease. serum level o...

background and objective: the aim of this study was to determine the level of plasma high sensitive c-reactive protein (hs-crp) in preeclampsia and to compare hs-crp levels between normal pregnant women, mild preeclamptic, and severe preeclamptic women. materials and methods: serum hs-crp levels were investigated in 40 cases of normal pregnant women, 37 cases with mild preeclampsia and 38 cases...

intravenous hydralazine is a commonly administered arteriolar vasodilator that is effective for hypertensive emergencies associated with pregnancy. oral nifedipine is an alternative in management of these patients. in this study the efficacy of nifedipine and hydralazine in pregnancy was compared in a group of iranian patients. fifty hypertensive pregnant women were enrolled in the study. a ran...

background: pre?eclampsia as a hypertensive disorder of pregnancy complicates up to 5–10% of pregnancies worldwide. endothelial dysfunction plays an important role in the pathogenesis of pre?eclampsia. in this study, we aim to evaluate the effect of high?dose folic acid on endothelial dysfunction in pre?eclamptic patients. materials and methods: in this triple?blinded randomized clinical trial,...