Background: According to high prevalence of renal stone in children, we evaluated the efficacy of treatment with potassium citrate and its correlation with metabolic disorders in children less than two years of age with renal stone and microlithiasis. Methods: In this cross- sectionaly study, 100 patients (less than 2 years old) with renal stone or microlitiasis were evaluated for metabolic di...

Urinary calculus is a common disease. Potassium citrate is usually used to prevent lithangiuria. Urinary calculus formation is affected by sex hormone. This study investigated the preventive and therapeutic effect of potassium citrate combined estradiol on lithangiuria. SD rats were randomly divided into three groups, control group, model group established by administration of 3% melamine (Mel)...

PURPOSE To study the effects of long-term treatment with potassium magnesium citrate and vitamin B-6 prophylaxis (Urikind-KM6; 1,100-mg potassium citrate, 375-mg magnesium citrate, and 20-mg pyridoxine hydrochloride/5 mL) every 8 hours over 3 years. MATERIALS AND METHODS A total of 247 patients with recurrent idiopathic hypocitraturia with or without hyperuricosuria and randomized controls we...

Primary Sjogren's Syndrome presenting as quadriplegia and respiratory involvement due to renal tubular acidosis causing hypokalemia is rare and the significance of managing such case with potassium citrate instead of potassium chloride is highlighted.

Extracellular pH (pHe) of tumor cells is characteristic microenvironment (TME). Acidic TME impairs the responses tumors to some anti-cancer chemotherapies. In this study, we showed that daily oral dosing sodium potassium citrate (K/Na citrate) increased blood HCO3− concentrations, corresponding increase concentrations and pHs in urine, neutralized pHe. Neutralization acidic by alkaline substanc...

Objective: Tooth hypersensitivity often starts in early adulthood because of gum recession and loss of the cementum covering dentin. The purpose of this study was to compare the effect of toothpaste,1 containing triclosan, potassium nitrate, zinc citrate,2 triclosan, potassium nitrate,3 calcium sodium phosphosilicate (novamin) on gingival health, plaque formation and dentin hypersensitivity in ...

The CIR Expert Panel (Panel) assessed the safety of citric acid, 12 inorganic citrate salts, and 20 alkyl citrate esters as used in cosmetics, concluding that these ingredients are safe in the present practices of use and concentration. Citric acid is reported to function as a pH adjuster, chelating agent, or fragrance ingredient. Some of the salts are also reported to function as chelating age...