AIM Developing antitumor drugs from natural products is receiving increasing interest worldwide due to limitations and side effects of therapy strategies for the second leading cause of disease related mortality, cancer. METHODS The antiproliferative activity of a methanolic extract from the aerial parts of Marrubium persicum extract was assessed with the MCF-7 breast cancer cell line using t...

Synthesis of Silver Nanoparticles using Methanol Extract Bunium Persicum and the Evaluation its Cytotoxic, Antileishmanial, Antimicrobial Activities

BACKGROUND AND OBJECTIVE: Emergence of resistant microbial strains due to the consumption of chemical preservatives and medications, as well as uncertainty about the consumption of foods containing synthetic preservatives, have resulted in the growing popularity of natural preservatives. This study aimed to identify the chemichal compounds found in the essence of Persian hogweed (Heracleum pers...

BACKGROUND Plant extracts and oils may act as alternatives to conventional pesticides for malaria vector control. The aim of this study was to evaluate the larvicidal activity of essential oils of three plants of Apiaceae family against Anopheles stephensi, the main malaria vector in Iran. METHODS Essential oils from Heracleum persicum, Foeniculum vulgare and Coriandrum sativum seeds were hyd...

The Czech botanist František Nábělek (1884-1965) explored the Middle East in 1909-1910, visiting what are now Israel, Palestine, Jordan, Syria, Lebanon, Iraq, Bahrain, Iran and Turkey. He described four new genera, 78 species, 69 varieties and 38 forms of vascular plants, most of these in his work Iter Turcico-Persicum (1923-1929). The main herbarium collection of Iter Turcico-Persicum comprise...

BACKGROUND The key enzyme in the process of melanin biosynthesis is tyrosinase. Skin hyperpigmentation and browning of foods are undesirable phenomena which tyrosinase represents. Therefore, tyrosinase inhibitors have been used increasingly for medicinal and cosmetic products. OBJECTIVES In this study, inhibitory effects of four plants including: physalis alkekengi L., Alcea rosea L., Bunium ...

Several pre-germination treatments were given to Cyclamen persicum Mill. seed with the objective of improving germination percentage, speed, and uniformity. Soaking seed in water and in gibberellic acid improved germination speed, but the latter reduced survival. Etridiozole, benomyl, thiram, and sodium hypochlorite treatments did not reduce or delay germination as has been reported elsewhere, ...

BACKGROUND A number of medicinal plants have been used to treat various immunological diseases. Nitric oxide (NO) has an important regulatory role in the various types of inflammatory processes. OBJECTIVE To investigate the NO modulatory activity of the extracts of several medicinal plants native to Iran including Dracocephalum kotschyi, Linum persicum, Dionysia termeana, Salvia mirzayanii, F...