Efficient and one-pot synthesis of 1,8-dioxo-octahydroxanthenes was described by Knoevenagel condensation, Michael addition and cyclodehydration of dimedone. This reaction was carried out through condensation of dimedone and various aromatic aldehydes in the presence of task-specific Brønsted acidic ionic liquid under solvent free conditions. The catalyst could be recycled five times without si...

a facile one-pot method with good yield for the synthesis of 2,4-dichloroquinoline and some related new derivatives by condensation of the appropriate primary aromatic amine with malonic acid in presence of excess phosphorus oxychloride is described.

3,4-ِdihydropyrano[c]chromene derivatives were synthesized using sulfonic acid functionalized silica (sio2-pr-so3h) as a highly efficient heterogenous solid acid catalyst via one-pot three-component condensation of aromatic aldehydes with malononitrile and 4-hydroxycoumarin in excellent yields.

Phosphosulfonic acid (PSA) was found to be an efficient catalyst for the one-pot three-component Hantzsch condensation reaction of arylaldehydes, ethylacetoacetate and ammonium acetate to afford the corresponding 1,4-dihydropyridine and polyhydroquinoline derivatives in high yields. PSA was also applied for the one-pot preparation of polyhydroquinolines via four-component reaction of a...

phosphosulfonic acid (psa) was found to be an efficient catalyst for the one-pot three-component hantzsch condensation reaction of arylaldehydes, ethylacetoacetate and ammonium acetate to afford the corresponding 1,4-dihydropyridine and polyhydroquinoline derivatives in high yields. psa was also applied for the one-pot preparation of polyhydroquinolines via four-component reaction of arylaldehy...

In this study a multicomponent reaction involving carbohydrate derivatives as the main component in order to prepare a new library of polyhydroxy compounds incorporating pyrimidine-fused heterocycles (PFHs) is introduced. A set of polyhydroxy functionalized PFHs were synthesized using multicomponent reactions of sugar (glucose, galactose, arabinose and lactose), barbituric acid and amines. Also...

A facile one-pot method with good yield for the synthesis of 2,4-dichloroquinoline and some related new derivatives by condensation of the appropriate primary aromatic amine with malonic acid in presence of excess phosphorus oxychloride is described.  

an efficient green route for the preparation of naphthoxazinones, applying a three-component one-pot condensation reaction of 2-naphthol, aromatic aldehyde and urea in the presence of nano silica supported ferric chloride under solvent-free conditions has been developed. the present procedure offers several advantages such as short reaction time, simple workup, recovery and reusability of the c...

sulfuric acid {[3-(3-silicapropyl)sulfanyl]propyl}ester (saspspe) is employed as a recyclable catalyst for the synthesis of α-amino nitriles. these syntheses were performed via a one-pot three-component condensation of aldehydes, amines, and trimethylsilyl cyanide under mild reaction conditions at room temperature. the catalyst could be recycled and reused several times without any loss of effi...

an efficient and direct procedure for the synthesis of benzo[h]-indeno[1,2-b]-quinoline derivatives has been described. the procedure employs a three-component condensation reaction in one-pot using 2h-indene-1, 3-dione, naphthalen-1-amine,and aldehydes in the presence of catalytic amount of l-prolinein aqueous media.