Subarachnoid hemorrhage (SAH) represents a considerable health problem with an incidence of 6-7 per 100.000 individuals per year in Western society. We investigated the long-term consequences of SAH on behavior, neuroinflammation and gray- and white-matter damage using an endovascular puncture model in Wistar rats. Rats were divided into a mild or severe SAH group based on their acute neurologi...

while a wide array of pathological changes occur in cerebral arteries following subarachnoid hemorrhage (sah), the most consistent is endothelial damage. since the endothelium normally modulates reflexes that influence vascular tone, any damage to it may represent a significant contributor to cerebral vasospasm following sah. this experimental study investigates the correlation between endothel...

BACKGROUND The authors are aware of only one article investigating amino acid concentrations in cerebrospinal fluid (CSF) in patients with ruptured intracranial aneurysms, and this was published 31 years ago. Since then, both management of subarachnoid haemorrhage (SAH) and amino acid assay techniques have seen radical alterations, yet the pathophysiology of SAH remains unclear. OBJECTIVE To ...

When seen after head trauma, subarachnoid hemorrhage (SAH) often leads to an angiogram to look for vascular injury. Usually the study is negative; sometimes a traumatic aneurysm or dissection is seen. Occasionally, a conventional saccular aneurysm is found. The clinical history, physical examination, and computed tomography (CT) scan in such a patient may suggest that an aneurysmal SAH was the ...

BACKGROUND AND PURPOSE We report the first case of traumatic aneurysm of the supraclinoid internal carotid artery (ICA), which we speculate may have developed or grown after traumatic occlusion of the ipsilateral cervical ICA. CASE DESCRIPTION A 26-year-old man presented with severe traumatic subarachnoid hemorrhage (SAH) and occlusion of the right cervical ICA after a motor vehicle accident....

BACKGROUND To investigate the frequency, predictors, and clinical impact of electrographic seizures in patients with high clinical or radiologic grade non-traumatic subarachnoid hemorrhage (SAH), independent of referral bias. METHODS We compared rates of electrographic seizures and associated clinical variables and outcomes in patients with high clinical or radiologic grade non-traumatic SAH....

background : ruptured cerebral aneurysms (icas) are the most common non-traumatic cause of subarachnoid hemorrhage (sah) that is associated with life threatening complications such as vasospasm, infarction, and hydrocephalus (hcp). the active participation of macrophage/monocyte-mediated inflammatory response in the pathogenesis of cerebral aneurysm as labeled with monocyte chemoattractantprote...

all people have experience about anxiety in their lives and it is natural when facing with reactional threatening situations. but chronic and intense feeling is unusual in absence of clear cause. anxiety includes uncertainty, helplessness and physiological arousal feelings. generally anxiety is a diffuse, very unpleasant and often vague concern feeling. clinical studies of war veterans over the...

objectives: the aim of this study was to evaluate the surgical approach in post traumatic diaphragmatic hernia. methods: this prospective cross-sectional study was conducted in the department of cardiovascular and thoracic surgery, sher-i- kashmir institute of medical sciences (skims), kashmir, india. we included all patients with post traumatic diaphragmatic hernia undergoing operation in our ...

BACKGROUND AND PURPOSE Subarachnoid hemorrhage (SAH) pathophysiology involves neurovascular proteolysis and inflammation. How these 2 phenomena are related remains unclear. We hypothesize that matrix metalloproteinases (MMPs) mediate the depletion of anti-inflammatory plasma-type gelsolin (pGSN). METHODS We enrolled 42 consecutive SAH subjects and sampled cerebrospinal fluid (CSF) and blood o...