We report on the mobilization of shuttle plasmids from gram-negative Escherichia coli to gram-positive corynebacteria mediated by P-type transfer functions. Introduction of plasmids into corynebacteria was markedly enhanced after heat treatment of the recipient cells. High-frequency plasmid transfer was also observed when the restriction system of the recipient was mutated. On the basis of our ...

Naphthyridones that were recently described as a class of translation inhibitors in gram-positive bacteria mediate their mode of action via GyrA in Haemophilus influenzae and Escherichia coli. These are the first examples of compounds in which modes of action in different bacterial pathogens are mediated through widely different targets.

cladophora and enteromorpha are the filamentous green-algal genuses that have a widespread distribution in caspian sea coast. the aim of this study was to assess the antimicrobial activities of cladophora and enteromorpha in south of caspian sea. antibacterial activities of hydroalcoholic extracts of five different gram negative and positive bacteria including staphylococcus aureus, bacillus su...