Here, we used a fluorophore-bound, porphyrin-targeted DNA aptamer to increase the sensitivity of capillary electrophoresis for detection model porphyrin. The complex wit...

Studies were conducted to define the specific changes in the urinary porphyrin excretion pattern (porphyrin profile) and the time course of those changes in rats exposed to mercury as methyl mercury hydroxide (MMH) at 5 or 10 ppm in the drinking water for up to 30 weeks. The urinary porphyrin profile elicited by MMH is uniquely characterized by highly elevated levels of 4- and 5-carboxyl porphy...

Starburst polyamidoamine (PAMAM) dendrimer is a new class of highly branched spherical polymer. Covalent attachment of porphyrin to PAMAM dendrimer may alter the pharmacokinetics, cell targeting, and photophysical properties of porphyrin. We investigated the uptake, localization, and phototoxicity of PAMAM-porphyrin conjugate with different charges and hydrophobicity in Hela cell lines. The cel...

A series of meso-meso, β-β, β-β triply linked linear, radial and square-type zinc(II) porphyrin arrays consist of the constituent porphyrin units and naphthalene junctions. To understand the unique nature of triply linked porphyrin arrays, numerous research activities have been focused on the electronic structures of the constituent porphyrin units. In this study, however, we have paid attentio...

In the past decade much effort has been devoted to the synthesis and studies of molecular systems comprising porphyrin units bridged by well-defined p-conjugated spacers at the mesoor b-positions. These conjugated oligoporphyrin systems are expected to have potential applications in molecular wires and electronic devices due to their unique optical, physical, and chemical properties. Photophysi...

Zinc-porphyrin-appended norbornene derivative 6, the corresponding dimer 7, coherently aligned single-stranded polynorbornene 5, and zinc-porphyrin-linked double-stranded polymeric ladderphane 3 have been used for complexation with 1,4-diazabicyclo[2.2.2]octane (DABCO) to generate an array of porphyrin-DABCO supramolecular scaffolds. The stoichiometries of the complex formation are analyzed in ...

The extent of triplet state delocalization is investigated in rigid linear zinc porphyrin oligomers as a function of interporphyrin bonding characteristics, specifically in meso-meso singly linked and β,meso,β fused structures, using electron paramagnetic resonance techniques. The results are compared with those of earlier measurements on porphyrin oligomers with alkyne linkers exhibiting diffe...

Five known porphyrins, 5,10,15,20-tetrakis(p-tolyl)porphyrin (TTP), 5,10,15,20-tetrakis(p-bromophenyl)porphyrin (TBrPP), 5,10,15,20-tetrakis(p-aminophenyl)porphyrin (TAPP), 5,10,15-tris(tolyl)-20-mono(p-nitrophenyl)porphyrin (TrTMNP), 5,10,15-tris(tolyl)-20-mono(p-aminophenyl)porphyrin (TrTMAP), and three novel porphyrin derivatives, 5,15-di-[bis(3,4-ethylcarboxymethylenoxy)phenyl]-10,20-di(p-t...

Single- and multiwalled carbon nanotubes have been covalently functionalized with free-base porphyrin. The quantity of porphyrin linked to the surface was determined from thermogravimetric and UV-vis analysis. A reversible protonation equilibrium between the attached porphyrin and the residual acid groups of the carbon nanotubes has been identified. Steady-state fluorescence emission spectrum o...

A diphenyl porphyrin substituted nucleotide was incorporated site specifically into DNA, leading to helical stacked porphyrin arrays in the major groove of the duplexes. The porphyrins show an electronic interaction which is significantly enhanced compared to the analogous tetraphenyl porphyrin (TPP) as shown in the large exciton coupling of the porphyrin B-band absorbance. Analogous to the TPP...