BACKGROUND Comedones are usually found in acne and involve the seborrheic areas of the skin. Disseminated comedones can be found in other skin disorders. Flexural comedones are characterized by double orifices connected by a thin layer of epidermis that reveals the comedo content below it. To the best of our knowledge, flexural comedones have not been previously described as an entity. Our obje...

IMPORTANCE Recent data demonstrated somatic mutations in GJB2 that were present in affected porokeratotic eccrine ostial and dermal duct nevus (PEODDN) tissue but absent in unaffected skin. Recognizing that PEODDN lesions can also appear in individuals with keratitis-ichthyosis-deafness syndrome and finding somatic mutations in their cohort, the authors concluded that somatic GJB2 mutation may ...

Indian Dermatology Online Journal July-August 2015 Volume 6 Issue 4 Address for correspondence: Dr. Krina B. Patel, Department of Dermatology, GMERS Medical College and Hospital, Sola, Ahmedabad, Gujarat, India. E‐mail: y2k_kbpatel@ yahoo.com Department of Dermatology, GMERS Medical College and Hospital, Sola, Ahmedabad, Gujarat, India A 47‐year‐old male patient presented with itchy skin lesion...