Fibrous dysplasia affects principally the bone, it might also comprise extra skeletal anomalies; whereby the bone is replaced by a dysplastic fibrous tissue. It is classified according to the number of affected bones, and its association to endocrine alterations in: monostotic, polyostotic forms and Albright's disease. A congenital etiology is suggested. Pathologic fractures are the most freque...

Fibrous dysplasia is classified among benign bone tumors. It is a bone development anomaly characterized by hamartoma proliferation of fibrous tissue within the medullary bone, with secondary bony metaplasia, producing immature, newly formed and weakly calcified bone, without maturation of the osteoblast. It can be monostotic or polyostotic. The craniofacial localization occurs in 10%-25% of ca...

Clinical, endocrinological and computed tomographic features of three patients with unusual manifestations or complications of craniofacial involvement of fibrous dysplasia are presented. One patient with polyostotic fibrous dysplasia presented in late pregnancy with acute onset of bilateral optic nerve compression and blindness secondary to a rapidly expanding mass of fibrous dysplasia tissue ...

Whole-body bone scans and whole body (18)F-fluorodeoxyglucose positron emission tomographic/computed tomographic scans are sensitive for detecting bone metastasis in patients with breast cancer. However, it is often difficult to discriminate between bone metastasis and other nonmalignant bone lesions. Polyostotic fibrous dysplasia is a rare disorder characterized by the osteoid medullary cavity...

717 ibrous dysplasia is a developmental anomaly that can affect any bone in the body. The skull and facial bones are the affected sites in 10–25% of patients with monostotic fibrous dysplasia and in 50% of patients with polyostotic fibrous dysplasia. Conventional radiographic findings reveal characteristics of fibrous dysplasia. CT findings also show characteristics of fibrous dysplasia and con...

The lesions of fibrous dysplasia usually stabilize after adolescence, and the surgical treatment of adult patient remains the mainstay. However, the surgical treatment alone may be not enough for patient with polyostotic fibrous dysplasia. We present the case of a surgically treated 36-year-old man with a diagnosis of progressive polyostotic fibrous dysplasia in the craniomaxillofacial region. ...

A patient with polyostotic fibrous dysplasia had several fractures of the right lower limb. An above-knee amputation was eventually performed, followed by arthrodesis of the hip. Five years later the stump became painful and swelled with dramatic rapidity. Biopsy showed that this was not due to malignant change, but that an aneurysmal bone cyst had developed in association with the fibrous dysp...

INTRODUCTION Involvement of the spinal column in either monostotic or polyostotic form is rare, with fewer than thirty-five cases discussed in the literature. Most of the cases of polyostotic fibrous dysplasia of spine have involvement of the appendicular skeleton. CASE REPORT We report a case of a 74-year-old Irish man with a two month history of back pain. Investigations revealed a diagnosi...