OBJECTIVE To determine how thermoregulation of the feet is affected by diabetes and diabetic polyneuropathy in both wakefulness and sleep. RESEARCH DESIGN AND METHODS Normal subjects, diabetic subjects without neuropathy, diabetic subjects with small-fiber diabetic polyneuropathy, and those with advanced diabetic polyneuropathy were categorized based on neurological examination, nerve conduct...

Copper is a cofactor for numerous coenzymes and metalloproteins essential for normal neurologic function. Th e most common neurological presentations of copper defi ciency are myelopathy, polyneuropathy and optic neuropathy. Here we present two cases of sensorimotor polyneuropathy, copper defi ciency and microcytic anemia in conjunction with allopurinol management for gout. Th ese two patients ...

BACKGROUND The independent contribution of levodopa exposure and Parkinson's disease (PD) to the risk of polyneuropathy is not established. OBJECTIVE This study investigated whether patients with newly diagnosed PD without previous exposure to antiparkinsonian drugs have higher prevalence of polyneuropathy than the general population. METHODS Using the UK General Practice Research Database,...

Corresponding author: Min Young Chung Division of Endocrinology and Metabolism, Department of Internal Medicine, Chonnam National University Medical School, 8 Hak-dong, Dong-gu, Gwangju 501-757, Korea E-mail: [email protected] We appreciate the interest and comments on our study, “Association between diabetic polyneuropathy and cardiovascular complications in type 2 diabetic patients,” whic...

how to cite this article: karimzadeh p, bakhshandeh bali mk, nasehi mm, taheri otaghsara sm, ghofrani m. atypical findings of guillain-barré syndrome in children. iran j child neurol autumn 2012;6(4):17-22.   abstract objective guillain-barre syndrome (gbs) is an immune-mediated polyneuropathy that occurs mostly after  prior infection. the diagnosis of this syndrome is dependent heavily on the ...

over the past three decades physicians have used light level laser therapy (lllt) for the management and the treatment of diabetic peripheral neuropathy and have obtained results that calls for further investigations. this study aimed to investigate the effectiveness of lllt in treatment of pain symptoms in patients with diabetic polyneuropathy. in this study 60 patients with diabetic periphera...

OBJECTIVE To report familial occurrence of polyneuropathy associated with monoclonal gammopathy. DESIGN Case reports. PATIENTS We describe 6 patients (3 pairs) with a polyneuropathy associated with IgM monoclonal gammopathy. Four of the 6 patients had a demyelinating polyneuropathy on neurophysiological examination. Three patients had elevated antibodies against myelin-associated glycoprote...

Critical illness polyneuropathy and critical illness myopathy are frequent complications of severe illness that involve sensorimotor axons and skeletal muscles, respectively. Clinically, they manifest as limb and respiratory muscle weakness. Critical illness polyneuropathy/myopathy in isolation or combination increases intensive care unit morbidity via the inability or difficulty in weaning the...

The prevalence of polyneuropathy in patients with monoclonal gammopathy of undetermined significance (MGUS) has been reported to be 10-50%. The majority of patients have a chronic, slowly progressive, distal, symmetric and predominantly sensory polyneuropathy. A caused relationship between polyneuropathy and immunoglobulin (Ig)M MGUS is better established than the relationship between polyneuro...

Five patients developed a severe motor and sensory polyneuropathy at the peak of critical illness (sepsis and multiorgan dysfunction complicating a variety of primary illnesses). Difficulties in weaning from the ventilator as the critical illness subsided and the development of flaccid and areflexic limbs were early clinical signs. However, electrophysiological studies, especially needle electr...