We report the design of an injectable synthetic and biodegradable polymeric biomaterial comprised of polyethylene glycol and a polycarbonate of dihydroxyacetone (MPEG-pDHA). MPEG-pDHA is a thixotropic physically cross-linked hydrogel, displays rapid chain relaxation, is easily extruded through narrow-gauge needles, biodegrades into inert products, and is well tolerated by soft tissues. We demon...

TiO2 is widely used in biomaterial implants. The topography, chemical and structural properties of titania surfaces are an important aspect to study. size nanoparticles synthetized by sol–gel method can influence the responses biological environment, using appropriate heat treatments different contents polymorphs be formed. Protein adsorption a crucial step for responses, involving, particular,...

Abstract It has proved challenging to represent the behavior of polymeric macromolecules as machine learning features for biomaterial interaction prediction. There are several approaches this representation, yet no consensus a universal representational framework, in part due sensitivity biomacromolecular interactions polymer properties. To help navigate process feature engineering, we provide ...

This current research reports the characterization of fibers from Posidonia oceanica L. (P. oceanica) for interest in usability as additive biomaterial polymer-based materials. The results revealed that cellulose content, density, and average fiber diameter P. were 45.35%, 1.15 g/cm3 238.41 μm, respectively. maximum degradation temperature, char yield activations energy found to be 318.8 ºC, 31...

Surface modification of biomaterial interfaces remains an active field of research with a clear aim to enhance and retain blood compatibility of blood-contacting medical devices. Issues such as activation of coagulation pathways, altered hemostasis, inflammatory responses, and thrombosis are potential clinical complications during blood interaction with artificial surfaces that needs to be addr...

Bioactive coatings are in high demand to control cellular functions for numerous medical devices. The objective of this in vitro study was to characterize for the first time fibroblast (fibrous scar tissue forming cells) adhesion and proliferation on an important polymeric biomaterial (silicone) coated with titanium using a novel ionic plasma deposition (IPD) process. Fibroblasts are one of the...

Synthetic polymer coatings are used extensively in modern medical devices and implants because of their material versatility and processability. These coatings are designed for specific applications by controlling composition and physical and chemical properties, and they can be formed into a variety of complex structures and shapes. However, implantation of these materials into the body elicit...