Objective : Eclipta alba (Asteraceae) is a traditional medicinal plant known as Bhringaraj.This plant has been used for the treatment of a variety of diseases. The leaves of Eclipta alba showed antihyperglycemic activity. The roots of Eclipta alba were found effective in wound healing . Methods : This study was undertaken to evaluate the possible antidepressant effect of Eclipta alba leaf extra...

Variola major, the causative agent of smallpox, has been eradicated from nature. However, stocks still exist; thus, there is a need for relevant decontamination studies, preferably with nonpathogenic simulants. Previous studies have shown a similarity in response of vaccinia virus and variola major to various decontaminants and thermal inactivation. This study compared vaccinia and fowlpox viru...

The present study was conducted to prepare sustained release microspheres of naproxen sodium using ethyl cellulose (Ethocel 20 cps) polymer. Three different plasticizers namely polyethyleneglycol 600 (PEG 600), polyethyleneglycol 6000 (PEG 6000) and triethyl citrate (TEC) were used at 10% (wt/wt) and 40% (wt/wt) level of the drug content. Prepared microspheres were characterized with respect to...

In contrast to the general assumption that polyethyleneglycol (PEG)-conjugated substances lack immunogenicity and antigenic, it has been reported that they can elicit antibodies against PEG (mainly anti-PEG immunoglobulin M (IgM)). In patients, the presence of anti-PEG antibodies may limit therapeutic efficacy of PEGylated substances as a consequence of inducing rapid clearance of and neutraliz...