The association of peculiar giant-cellular granulomatous lesions of the upper respiratory tract and the lungs or other organs with necrotizing vascular lesions resembling polyarteritis nodosa has been seldom reported. Klinger (1931) described one case; R6ssle (1936) one case; Wegener (1939) three case-s; Neumann (1940) four cases; Banowitch, Polayes, and Charet (1942) one case; Lindsay, Aggeler...

Polyarteritis nodosa has been the subject of comprehensive reviews covering most of its clinical and histological aspects (Smith and Zeek, 1947; Miller and Daley, 1946; Davson, Ball, and Platt, 1948). There are, however, four points which require clarification, and they are discussed in the present paper: (1) the early changes and the question of the so-called "fibrinoid " substance; (2) some h...

A necrotizing arteritis in the uterine cervix is described as an incidental finding in surgical material from 10 patients. The histological features are compared with those seen in polyarteritis nodosa. Subintimal hyaline deposition and a relative paucity of neutrophil and eosinophil polymorphs characterized the lesion but the histological appearance was never sufficiently specific to exclude c...

A case of an 18 year old woman is reported who presented with a pyrexia of unknown origin having returned from a trip to India. She initially had constitutional symptoms only, which rapidly progressed to a multisystem disorder. The difficulty in making the diagnosis of polyarteritis nodosa, especially with the possible differential diagnosis of infection after her recent travel, is discussed. T...

Medium-sized vessel vasculitis such as Kawasaki disease and polyarteritis nodosa (PAN) were discussed. Kawasaki disease is characterised by fever, strawberry tongue, cervical lymphadenopathy, erythema or oedema of palms and soles, and periungal desquamation in the subacute phase. Polyarteritis nodosa may be systemic or cutaneous. Symptoms and signs may include livedo reticularis, subcutaneous n...

Two young men, were hospitalized due to acute massive blood loss with left abdominal flank pain. In both cases renal angiography showed signs of a haemorrhagic event in the left kidney, perirenal in one and subcapsular in the other. Microaneurysms indicated a diagnosis of polyarteritis nodosa, supported by renal biopsy in one case. Renal haemorrhage is an infrequent presentation of polyarteriti...

Hemobilia, in patients with the diagnosis of polyarteritis nodosa, is rare at clinical presentation and has a grave prognosis. We describe a case of massive hemobilia, due to aneurysmal rupture, in a patient with polyarteritis nodosa. A 39-year-old man was admitted to the hospital with upper abdominal pain. The patient had a history of partial small bowel resection, for intestinal infarction, a...

Polyarteritis nodosa with gallbladder involvement is a rare condition. Autosomal dominant polycystic kidney disease is also a rare condition and rarely complicated. We describe an extremely rare case of Polyarteritis nodosa, involving gallblader and ureter without obstruction, in a patient with autosomal dominant polycystic kidney disease. To the best of the authors’ knowledge, such a case has ...

POLYARTERITIS NODOSA is a disease in which widespread acute necrosis occurs in the arteries, leading to a variety of functional disturbances involving the nervous system, heart, kidneys, lungs, abdominal viscera, and blood (Harvey, 1959). The liver is affected in this condition more frequently than is recognized. The following case report illustrates the need for care in the administration of m...