The emergence of porcine circovirus type 2 (PCV2) associated diseases and particularly postweaning multisystemic wasting syndrome (PMWS) was a shock for the swine industry and formulated a considerable challenge for researchers in the area of viral immunology in swine. The unique features of PMWS of which emaciation and lymphoid depletion were the most evident indicated a deep involvement of th...

Porcine Circovirus Diseases (PCVD) and Porcine Circovirus Associated Disease (PCVAD) are synonymous names for a disease syndrome caused by porcine circovirus type 2 (PCV2) and originally described in the mid-1990’s as Postweaning Multisystemic Wasting Syndrome (PMWS). 2 While the acronyms PCVD and PMWS have been widely used over the last decade, the American Association of Swine Veterinarians i...

The development of high-throughput sequencing technologies have allowed the possibility to investigate and characterise the entire microbiome of individuals, providing better insight to the complex interaction between different microorganisms. This will help to understand how the microbiome influence the susceptibility of secondary agents and development of disease. We have applied viral metage...

Postweaning wasting is a major worldwide problem in pig production, particularly with respect to the disease termed postweaning multisystemic wasting syndrome (PMWS). In addition to wasting, PMWS symptoms include respiratory distress, diarrhoea, pallor and occasional cases of jaundice. The causative agent is porcine circovirus type 2 (PCV-2). The objective of the present study was to determine ...

Once a diagnosis of herd Post-weaning Multisystemic Wasting Syndrome (PMWS) is made, (which can be difficult), a control and treatment programme of enhanced management must be immediately implemented. This programme is likely to be more intense than anything the farm health team has ever undertaken previously. As the causal agent of PMWS is not yet recognized, control has to be non-specific. Th...

The study assessed the economic efficiency of different strategies for the control of post-weaning multi-systemic wasting syndrome (PMWS) and porcine circovirus type 2 subclinical infection (PCV2SI), which have a major economic impact on the pig farming industry worldwide. The control strategies investigated consisted on the combination of up to 5 different control measures. The control measure...

John C. S. Harding Department of Large Animal Clinical Sciences Western College of Veterinary Medicine University of Saskatchewan Introduction Since its discovery and characterization in western Canada in 1995, the significance and dissemination of post-weaning multisystemic wasting syndrome (PMWS) has grown and the syndrome is undoubtedly a serious issue in the global swine industry. More rece...

Presence of porcine circovirus type 1 (PCV1) and PCV2 was studied in sera and superficial inguinal lymph nodes from postweaning multisystemic wasting syndrome (PMWS)-affected and non-PMWS-affected pigs by using in situ hybridization and PCR. PCV1 and PCV2 were found in less than 3% and more than 50% of the samples, respectively. The most sensitive technique and site was PCR in superficial ingui...

The objective of this study was to determine the serum concentration levels of selected acute phase proteins (APP), haptoglobin (HPT) and pig-major acute phase protein (pig-MAP), in postweaning multisystemic wasting syndrome (PMWS) affected pigs and PCV2-subclinically infected pigs. In a first study, a group of 15 eight-week-old conventional pigs from a PMWS affected farm were bled and a comple...

Postweaning multisystemic wasting syndrome (PMWS) has been recognized worldwide and is characterized clinically by wasting, dyspnea, and occasionally by icterus in nursery and grow-finish pigs. Type 2 porcine circovirus (PCV2) is consistently demonstrated in PMWS lesions. At the Iowa State University Veterinary Diagnostic Laboratory, both porcine reproductive and respiratory syndrome virus (PRR...