نتایج جستجو برای: pluripotent stem cells

تعداد نتایج: 1506620  

Journal: مجله علوم اعصاب شفای خاتم 2018
Karim Nikkhah,

Neurodegenerative diseases are the hereditary and sporadic diseases which are characterized by progressive neuronal loss of the nervous system and are emerging as the leading cause of death, disabilities, and a socioeconomic burden due to an increase in life expectancy. There are many neurodegenerative diseases including Alzheimer’s disease, Parkinson’s, disease, amyotrophic lateral...

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Journal: :international journal of pediatrics 0
mina shahriari cell and molecular biotechnology research group, institute of biotechnology, ferdowsi university of mashhad, mashhad, iran. zahra hejazi cell and molecular biotechnology research group, institute of biotechnology, ferdowsi university of mashhad, mashhad, iran. moein farshchian cell and molecular biotechnology research group, institute of biotechnology, ferdowsi university of mashhad, mashhad, iran. hojjat naderi cell and molecular biotechnology research group, institute of biotechnology, ferdowsi university of mashhad, mashhad, iran. hamid reza bidkhori cell and molecular biotechnology research group, institute of biotechnology, ferdowsi university of mashhad, mashhad, iran. mahdi mir-ahmadi cell and molecular biotechnology research group, institute of biotechnology, ferdowsi university of mashhad, mashhad, iran.

regenerative capacity of mammals is limited and can rarely regenerate a specific organ or tissue fully. due to these limitations, regenerative medicine seeks efficient and safe cell sources for regeneration of damaged tissues and organs or treatment for incurable diseases. human embryonic stem cells (hescs) hold two important properties called self renewal and pluripotency. however, the use of ...

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Journal: :مجله علوم اعصاب شفای خاتم 0
sajad sahab negah a. shefa neuroscience research center, khatam alanbia hospital, tehran, iran b. histology and embryology group, basic science department, faculty of veterinary medicine, shiraz university, shiraz, iran zabihollah khaksar histology and embryology group, basic science department, faculty of veterinary medicine, shiraz university, shiraz, iran elham mohammad zadeh shefa neuroscience research center, khatam alanbia hospital, tehran, iran mostafa modarres mousavi shefa neuroscience research center, khatam alanbia hospital, tehran, iran ali jahanbazi jahan-abad shefa neuroscience research center, khatam alanbia hospital, tehran, iran

a common pathological process that occurred after brain injury is gliosis. gliosis involves the activation of glial cells to proliferate and become hypertrophic to occupy the injured brain areas. in order to form a defense system against the invasion of micro-organisms and cytotoxins into surrounding tissue, glial cells including astrocytes and microglia undergo reactive response to injury. neu...

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Journal: :international journal of reproductive biomedicine 0
karim nayernia jae ho lee wolfgang engel jessica nolte nadja drusenheimer kristina rathsack

germline and somatic stem cells are distinct types of stem cells that are dedicated to reproduction and somatic tissue regeneration, respectively. germline stem cells (gscs), which can self-renew and generate gametes, are unique stem cells in that they are solely dedicated to transmit genetic information from generation to generation. we developed a strategy for the establishment of germline st...

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ژورنال: مجله دانشکده پزشکی دانشگاه علوم پزشکی تهران 2016
حسینی برشنه, علی, رودبارانی, رضا, سلطانی, دانش, مدرسی, محمد حسین,

Stem cells are undifferentiated and multi pluripotent cells which can differentiate into a variety of mature cells and tissues such as nervous tissue, muscle tissue, epithelial tissue, skeletal tissue and etc. Stem cells from all different source have three unique features: 1) Proliferative capability: Stem cells are capable of self dividing and self renewing for long periods or more than six m...

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Journal: :avicenna journal of medical biotechnology 0

spermatogonial stem cell (ssc) technologies provide multiple opportunities for research in the field of biotechnology and regenerative medicine. the therapeutic use of embryonic stem cells (escs) is restricted due to severe ethical and immunological concerns. therefore, we need a new pluripotent cell type. despite well-known role of germ cells in the gametogenesis, some facts apparently show th...

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Journal: :Haematologica 2015
Isabel Dorn Katharina Klich Marcos J Arauzo-Bravo Martina Radstaak Simeon Santourlidis Foued Ghanjati Teja F Radke Olympia E Psathaki Gunnar Hargus Jan Kramer Martin Einhaus Jeong Beom Kim Gesine Kögler Peter Wernet Hans R Schöler Peter Schlenke Holm Zaehres

Epigenetic memory in induced pluripotent stem cells, which is related to the somatic cell type of origin of the stem cells, might lead to variations in the differentiation capacities of the pluripotent stem cells. In this context, induced pluripotent stem cells from human CD34(+) hematopoietic stem cells might be more suitable for hematopoietic differentiation than the commonly used fibroblast-...

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Journal: International Journal of Fertility and Sterility 2011
Arauzo-Bravo Balbach ST Esteves TC Houghton F Jauch A Pfeiffer MJ Stehling M

Studies on cell fusion-mediated nuclear reprogramming have led to the breakthrough of the induced pluripotent stem (iPS) cell technology. While this technology has neared stem cells to applications more than any other method, the mechanistic bases of reprogramming remain largely unsolved. In this context, comparative studies of oocyte and cell fusion-mediated reprogramming hold the greatest pro...

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Journal: :International Journal of Human Genetics 2022

The cells can divide and differentiate into several types of in an organism. It is not able to as the extraembryonic tissues, which are termed ‘pluripotent cells’. transcription factors such as, SOX-2, C-MYC, OCT-4 KLF-4 involved maintenance pluripotency. Pluripotent stem (PSCs) self-renewal cells, may be either induced pluripotent (iPSCs) or embryonic (ESCs). used treatment diseases like cance...

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Journal: :cell journal 0
morteza abouzaripour parichehr pasbakhsh nader atlasi abdol hossein shahverdi reza mahmoudi iraj ragerdi kashani

background: bone marrow has recently been recognized as a novel source of stem cells for the treatment of wide range of diseases. a number of studies on murine bone marrow have shown a homogenous population of rare stage-specific embryonic antigen 1 (ssea-1) positive cells that express markers of pluripotent stem cells. this study focuses on ssea-1 positive cells isolated from murine bone marro...

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