The presently acknowledged onset of synaptogenesis in the chick retina from embryonic day 12 (E12) onward stands in contrast with the appearance of spontaneous electrical activity, of presynaptic proteins, or of neurotransmitters during early formation of the inner (E6-E8) and outer (E9) plexiform layers. Therefore, we investigated the chick retina from E6 to E12 at which age first synapses app...

Plexiform schwannoma is a rare benign neoplasm of the neural sheath characterized by a multinodular plexiform growth pattern. The tumor usually occurs as an isolated finding, although rare cases have been reported in association with neurofibromatosis type 2 (NF2). A 25-year-old man was admitted for foot drop. He had an asymptomatic skin-colored nodule on his neck that had been present for 10 y...

Plexiform schwannoma is an unusual peripheral nerve sheath tumor. It can mimic plexiform neurofibroma. A five-year-old girl presented with painful swelling in left lumbar region. Radiologic investigations showed a multinodular tumor in the subcutaneous plane of lumbosacral region. A complete excision and histopathologic examination revealed a plexiform tumor composed of hypocellular and hyperce...

Gastrointestinal stromal tumors (GISTs) have a rather wide morphologic spectrum. Here, we report a rare variant plexiform GIST in gastric antrum. Microscopically, the tumor showed plexiform or multinodular growth pattern, proliferation of spindle cells, presence of epithelioid cells, and abundant myxoid stroma with thin-walled blood vessels. The histologic features were similar to plexiform fib...

Schwannomas are the most common benign neoplasms of the peripheral nerves in the upper extremity originating from the schwann cells of nerve sheath. They account for 5% of all tumours in upper extremity. Schwannomas are usually solitary, encapsulated and homogeneous masses and present with slowly growing masses, sometimes associated with pain and paresthesia. Pre-operative evaluation is based o...

Plexiform neurofibroma is a rare, poorly defined benign tumor of the peripheral nerve sheath. It spreads out just under the skin, or deeper in the body, and occurs exclusively in patients with neurofibromatosis type I. Facial plexiform neurofibroma may produce various degrees of cosmetic and functional deformities in the head and neck region. It is a virtually pathognomonic and often disabling ...

Plexiform Xanthomatous Tumor (PXT) is a rare benign tumor occurring in the dermis and subcutis composed of xanthomatous cells arranged in a distinct plexiform pattern. This condition has been found to occur exclusively in males. A rare occurrence of multiple plexiform xanthomatous tumors in a young female clinically diagnosed as multiple neurofibromatoses is presented. Literature search reveale...