M e t h o d s Data sources: Cochrane Controlled Trials Register (Issue 4, 2001), MEDLINE (1980 to June 2002), EMBASE/Excerpta Medica (1980 to May 2002), bibliographies of relevant studies, and contacting experts. Study selection and assessment: Randomized controlled trials (RCTs) in any language of patients > 16 years of age having pleurodesis for pleural effusion in the context of metastatic c...

BACKGROUND It has been suggested that talc and doxycycline might be acting through different pathways in creating pleurodesis. We hypothesized that combining doxycycline and talc in half the usual doses would be synergistic in inducing pleurodesis. METHODS Thirty-two rabbits were equally allocated into four groups: group 1, half-dose combination (5 mg/kg of doxycycline and 200 mg/kg of talc s...

OBJECTIVE Thoracic echography easily detects the sign of 'pleural sliding', due to the movement of the visceral pleura on the parietal pleura. This sign is absent when pleurodesis is present. This study was designed to test thoracic echography in the assessment of difference in pleurodesis obtained after abrasion or pleurectomy performed for spontaneous pneumothorax, mainly based on the presenc...

PURPOSE This study was conducted to evaluate the success rate of management of advanced. Lung cancer patients with malignant pleural effusion comparing talc powder with tetracycline for pleurodesis. PATIENTS AND METHODS We report 60 patients with lung cancer associated with malignant pleural effusion treated in the department of surgery NCI, Cairo University, between January. 1998 and Februar...

Pleurodesis is a definitive management strategy in malignant pleural effusion, its history briefly described, and narrative review made about indication, patient selection, response predictors benefits.

BACKGROUND & OBJECTIVES Chemical pleurodesis is an accepted therapy for patients with recurrent pleural effusions and pneumothorax. Iodopovidone has been shown to be safe and effective for chemical pleurodesis in several studies. The aim of this systematic review was to update a previously reported meta-analysis on the efficacy and safety of iodopovidone pleurodesis. METHODS Two databases MED...

Malignant pleural effusions are often symptomatic and tend to recur after simple aspiration. Pleurodesis may prevent recurrence of the effusion; many agents and techniques have been described. A questionnaire was sent to 448 clinicians in the United Kingdom to determine how pleurodesis is performed in practice. There was a 56% overall response, with replies from 101 respiratory physicians, 88 g...

slurry or thoracoscopic talc poudrage pleurodesis. Furthermore, it remains unclear whether spontaneous pleurodesis with TPC prolongs life. In survivors to 14 weeks, the mean time to pleurodesis was 54 days. One coauthor’s earlier study revealed that those with TPC who had spontaneous pleurodesis lived over 3 times as long as those who did not have pleurodesis [2] . If pleurodesis by itself prol...

Secondary pneumothorax commonly encountered and it often recurs or becomes a refractory to treatment. Pleurodesis is usually selected for initial treatment in community hospitals. Recently, endobronchial intervention using the endobronchial Watanabe spigot and endobronchial valve for refractory pneumothorax has become available, but these procedures can be performed only at a few institutions w...