Extramedullary hematopoietic effusion (EHE) is one of the extremely rare phenomena associated with extramedullary hematopoiesis, which caused by serous effusions, including pleural effusion, and may be related to hematologic disorders neoplasms. Herein, we present case an 81-year-old man EHE accompanying Waldenström's macroglobulinemia (WM). The patient complained anemia dyspnea. chest X-ray co...

A pilot study of topical (intrapleural) treatment with Corynebacterium parvum was carried out in 10 patients with malignant pleural effusions complicating primary or secondary neoplasms and necessitating frequent thoracocentesis for symptomatic relief. The method was aspiration of all intrapleural fluid except a small portion left for dilution, and then injection of 7 mg of a preparation of Cor...

Malignant Pleural Mesothelioma is a rare tumour that arise from the mesothelial cells of the pleura and in recent time the incidence of this disease is rising. Because of the implications for management and therapy, it is important to assess the accurate staging. 18F-fluorodeoxiglucose Positron Emission Tomography (18F-FDG PET) is become a useful tool in the diagnosis of many neoplasms, such as...

Thymic epithelial tumors (TET) are rare mediastinal neoplasms that can metastasize to the pleural space (stage IVA). Complete surgical resection remains the backbone of therapy for patients with early stage TET, however, the role of surgery in the management of patients with stage IVA disease is not fully defined. Published reports in this regard are mainly small, retrospective, and uncontrolle...

Multiple myeloma is a common hematological malignancy. Serous effusions are described uncommonly in myelomas. A myelomatous effusion however, is extremely rare and carries a poor prognosis. We report a case of multiple myeloma with leukemic transformation and simultaneous pleural fluid involvement in a 66-year old patient who was receiving chemotherapy. The patient developed exceptional dyspnea...

Pseudo-Meigs' syndrome is used to describe cases of ascites and/or pleural effusion associated with ovarian neoplasms other than benign tumors, which improve after removal of the ovarian lesion. We present three cases of pseudo-Meigs' syndrome secondary to ovarian metastasis from colorectal cancer. In case 1, the patient has severe dyspnea and hypoxia due to massive right pleural effusion; ther...

Myeloid/lymphoid neoplasms with FGFR1 rearrangement (MLN-FGFR1) comprise a heterogeneous group of that can present as myeloproliferative neoplasm, myelodysplastic/myeloproliferative acute myeloid leukemia, T or B lymphoblastic leukemia/lymphoma, mixed phenotype leukemia. The overall outcome these is poor, and patients often show cytogenetic evolution gain additional chromosomal abnormalities le...

The World Health Organization (WHO) recently published new guidelines for the diagnosis and classification of lung pleural tumors. This review provides a concise overview key updates, including discussions histologic features recommended terminology small diagnostic samples, revised grading system adenocarcinoma with inclusion complex glandular filigree micropapillary patterns, molecular large ...