objective: at present, growth factor-containing products such as enamel matrix derivatives, recombinant bone morphogenetic protein (rh-bmp), recombinant platelet derived growth factor and platelet rich plasma (prp) have gained increasing attention. prp is an autologous source of platelet growth factors used to enhance healing of soft and hard tissues. prp has gained popularity due to its autolo...

background the platelet-rich plasma (prp) and hyaluronic acid (ha) constitute a system of tissue growth that can regenerate damaged tissue. this study was performed to evaluate the effect of prp and ha in treatment of complications of achilles tendon reconstruction. methods we selected ten patients affected by achilles tendon injuries resulting from post-surgical complications subsequent to ten...

background clinical tendon injuries represent serious and unresolved issues of the case on how the injured tendons could be improved based on natural structure and mechanical strength. the aim of this studies the effect of aquatic activities and alogenic platelet rich plasma (prp) injection in healing achilles tendons of rats. methods forty rats were randomly divided into 5 equal groups. sevent...

background:the utility and efficacy of novel materials in tissue regeneration and antimicrobial therapy are contingent upon the employment of either blood derivatives rich in platelets or platelet-poor-plasma (ppp). this effect is largely mediated by the increased or decreased concentration of platelets in the plasma. the current study aimed to analyze and evaluate the impact of platelet-rich (...

objective(s): platelet-rich plasma (prp) has recently emerged as a promising strategy in regenerative medicine due to its multiple endogenous growth factors. little is known about the role of prp as a promoter in chondrogenesis of human adipose derived stem cells (hadscs). the aim of this study was to determine whether prp may be considered as a natural and easy achievable source of growth fact...

the purpose of the present randomized clinical trial study was to compare the effectiveness of bovine porous bone mineral (bpbm) with and without plasma rich in growth factors (prgf) in the treatment of mandibular class ii furcation defects.in seven patients, nine pairs of symmetric buccal or lingual mandibular class ii furcation defects were treated. in each patient, one defect received bpbm (...

conclusions both l-prp and l-prf could be used to effectively promote the healing of articular cartilage defects of the knee. results mean macroscopic scores of the treated defects were higher than the controls at all sampling times with significant differences (p < 0.05) observed between l-prf treated and control defects (10.13 vs. 8.37) and l-prp treated and control defects (10 vs. 8.5) at 4 ...

introduction: vesicovaginal fistula remains a challenge in surgical therapy. in this study autologous platelet rich plasma and platelet rich fibrin glue were used as a minimally invasive approach for vesicovaginal fistula closure. materials and methods: data including age, parity, iciq-ui (international consultation on incontinence questionnaire-urinary incontinence), iciq-qol (international co...

introduction intra-articular injections of platelet rich plasma (prp) for the treatment of knee osteoarthritis have been shown to reduce pain and improve joint function. the aim of this study is to examine the joint function by adding intra-articular growth hormone to platelet rich plasma. this study was performed on the individuals with knee osteoarthritis and under ultrasound guidance. conclu...