نتایج جستجو برای: platelet
تعداد نتایج: 115670 فیلتر نتایج به سال:
background: the purpose of the present in vitro study was to evaluate the effect of long term storage of conventional platelet concentrates (pcs) on major platelet receptors cd42b and cd41/cd61 by flow cytometry method and also measuring the overall platelet procoagulant activity status using platelet factor 3 (pf3) assay. materials and methods: six random units of conventional platelet concent...
Preparations of platelet concentrates (PCs) that are stored under blood bank conditions and used for transfusion purposes, appear to be enriched in platelet derived-microparticles (PMPs) with high coagulant activity that may change platelet efficacy and safety issues. High shear stress could cause shedding of PMPs from the platelet plasma membrane, platelet aggregation, and activation of the co...
background: platelet preparations have been used for a wide variety of clinical applications such as hemorrhage, tissue engineering and cellular therapy. platelet concentrates can be prepared by the apheresis method or from the whole blood using the buffy-coat or platelet-rich plasma methods. the purpose of this study was to compare four variations of platelet-rich plasma method based on double...
Background: Mean platelet volume (MPV) is associated with platelet reactivity. Large platelets contain more thrombogenic factors than small ones. Previous studies have shown platelet reactivity in patients with pulmonary thromboembolism (PTE).The aim of this study was to investigate the mean platelet volume (MPV) and platelet count in patients with PTE and healthy control subjects. Methods ...
Background: Patients undergoing cardiac surgery are at increased risk of bleeding due to multifactorial coagulopathies. In the present study, we aimed at investigating the changes in platelet count and function during and after surgery as well as determining the association of the platelet dysfunction with bleeding and transfusion requirements in these patients. Methods: A total o...
Background: The purpose of the present in vitro study was to evaluate the effect of long term storage of conventional platelet concentrates (PCs) on major platelet receptors CD42b and CD41/CD61 by flow cytometry method and also measuring the overall platelet procoagulant activity status using platelet factor 3 (PF3) assay. Materials and Methods: Six random units of conventional platelet conce...
Abstract Background and Objectives Immune platelet refractoriness is a complication of blood transfusion in patients with multiple platelet transfusions. Antibodies against surface antigens, including human platelet antigens (HPAs) and human leukocyte antigens (HLAs), can be produced which can cause the degradation of transfused platelets by macrophages. In this study, the frequency of platele...
ABSTRACT A large number of drugs have been demonstrated to effect platelet function and production .Even when shown to alter platelet function following ingestion of these drugs ,information on the effect of hematological parameter and the clinical significance is unavailable for many drugs. There is a lot of evidence in favour of significant changes in the activity of platelet function by vit...
Background Platelets have an important contribution in pathogenesis of different infectious and inflammatory disorders. This study was performed to identify the diagnostic value of platelet count (PLT), and platelet indices in children with acute pyelonephritis (APN). Materials and Methods In a cross sectional case control s...
conclusions tissue engineering may open a new window in cleft palate reconstruction. stem cells and growth factors play key roles in this field. results we reported a summary of the key-points concerning cleft palate development, the genes involving this defect, current therapeutic strategies, recently novel aspects, and future advances in treatments for easy and fast understanding of the conce...
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